1: 1-bromo-butane With magnesium in tetrahydrofuran T=40°C; 2 h; 2: N-benzyloxycarbonyl-L-aspartic anhydride in tetrahydrofuran T=-78°C; 4 h; 3: With citric acid in tetrahydrofuran T=-78 - 20°C; Title compound not separated from byproducts;
参考文献
Deguest, Geoffrey; Bischoff, Laurent; Fruit, Corinne; Marsais, Francis
Tetrahedron Asymmetry, 2006 , vol. 17, # 14 p. 2120 - 2125
1: 3-methoxybromobenzene With magnesium in tetrahydrofuran T=40°C; 2 h; 2: N-benzyloxycarbonyl-L-aspartic anhydride in tetrahydrofuran T=-78°C; 4 h; 3: With citric acid in tetrahydrofuran T=-78 - 20°C; Title compound not separated from byproducts;
参考文献
Deguest, Geoffrey; Bischoff, Laurent; Fruit, Corinne; Marsais, Francis
Tetrahedron Asymmetry, 2006 , vol. 17, # 14 p. 2120 - 2125
