H-AIB-OT BU.盐酸盐合成路线 （共 4 条）
反应条件
5 palladium on charcoal; hydrogen in dichloromethane T=20°C; Inert atmosphere;
参考文献
Ceccacci, Francesca; Mancini, Giovanna; Rossi, Paola; Scrimin, Paolo; Sorrenti, Alessandro; Tecilla, Paolo
Chemical Communications, 2013 , vol. 49, # 86 p. 10133 - 10135
反应条件
hydrogen; palladium 10 on activated carbon in ethyl acetate T=20°C; P=3677.86 Torr; 18 h;
参考文献
MERCK SERONO S.A.; BOMBRUN, Agnes; QUATTROPANI, Anna; GONZALEZ, Jerome; DORBAIS, Jerome; KNIGHT, Chris; BAKER-GLENN, Charles
Patent: WO2012/4287 A1, 2012 ;
Location in patent: Page/Page column 77 ;
WO 2012/004287 A1
反应条件
perchloric acid 7 h; Ambient temperature;
参考文献
Bavetsias, Vassilios; Jackman, Ann L.; Marriott, Jonathan H.; Kimbell, Rosemary; Gibson, William; Boyle, F. Thomas; Bisset, Graham M. F.
Journal of Medicinal Chemistry, 1997 , vol. 40, # 10 p. 1495 - 1510
反应条件
1: potassium carbonate; sodium hydrogencarbonate / N,N-dimethyl-formamide; acetonitrile / 20 °C 2: hydrogen / palladium 10 on activated carbon / ethyl acetate / 18 h / 20 °C / 3677.86 Torr View Scheme
参考文献
MERCK SERONO S.A.; BOMBRUN, Agnes; QUATTROPANI, Anna; GONZALEZ, Jerome; DORBAIS, Jerome; KNIGHT, Chris; BAKER-GLENN, Charles
Patent: WO2012/4287 A1, 2012 ;
WO 2012/004287 A1
