alpha-酮基异己酸钠盐合成路线 （共 17 条）
反应条件
water; sodium hydroxide T=100°C; 5 h;
参考文献
Lichtenecker, Roman J.; Weinhaeupl, Katharina; Reuther, Lukas; Schoerghuber, Julia; Schmid, Walther; Konrat, Robert
Journal of Biomolecular NMR, 2013 , vol. 57, # 3 p. 205 - 209
反应条件
sodium hydroxide in tetrahydrofuran; water 18 h; Ambient temperature;
参考文献
Ramage, Robert; Griffiths, Gareth J.; Shutt, Fiona E.; Sweeney, John N. A.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1984 , # 7 p. 1531 - 1537
参考文献
Kelly; Kelly, Nicholas M.; Reid; Gordon Reid; Willis; Willis, Christine L.; Winton; Winton, Peter L.
Tetrahedron Letters, 1995 , vol. 36, # 45 p. 8315 - 8318
反应条件
formate dehydrogenase; NADH-H+; 15N-ammonium formate; leucine dehydrogenase; DL-threo-1,4-dimercapto-2,3-butanediol Ambient temperatureTRIS, pH=6.5-7.0, 0.1M HCl;
参考文献
Kelly, Nicholas M.; O'Neill, Bridget C.; Probert, John; Reid, Gordon; Stephen, Rosamund; et al.
Tetrahedron Letters, 1994 , vol. 35, # 35 p. 6533 - 6536
反应条件
Ca(OCl)2; acetic acid in dichloromethane; water 2 h; Ambient temperature;
参考文献
Nwaukwa, Stephen O.; Keehn, Philip M.
Tetrahedron Letters, 1982 , vol. 23, # 31 p. 3135 - 3138
反应条件
Zn(ClO4)2; (R)-15-amino-methyl-14-hydroxy-5,5-dimethyl-2,8-dithialt;9gt;(2,5)pyridinophane in methanol 24 h; Ambient temperature;
参考文献
Tachibana, Yoji; Ando, Makoto; Kuzuhara, Hiroyoshi
Chemistry Letters, 1982 , p. 1765 - 1768
反应条件
Zn(ClO4)2; (S)-15-aminomethyl-14-hydroxy-2,8-dithialt;9gt;(2,5)pyridinophane in methanol 576 h; Ambient temperature; Yield given. Yields of byproduct given. Title compound not separated from byproducts;
参考文献
Ando, Makoto; Kuzuhara, Hiroyoshi
Bulletin of the Chemical Society of Japan, 1989 , vol. 62, # 1 p. 244 - 250
反应条件
Zn(ClO4)2; (S)-15-amino-methyl-14-hydroxy-5,5-dimethyl-2,8-dithialt;9gt;(2,5)pyridinophane in methanol 24 h; Ambient temperature;
参考文献
Chemistry Letters, , p. 1765 - 1768
反应条件
Zn(ClO4)2; (S)-15-aminomethyl-14-hydroxy-2,8-dithialt;9gt;(2,5)pyridinophane in methanol 576 h; Ambient temperature; Yield given. Yields of byproduct given. Title compound not separated from byproducts;
参考文献
Bulletin of the Chemical Society of Japan, , vol. 62, # 1 p. 244 - 250
反应条件
hydrogenchloride; water in tert-butyl methyl ether T=0°C;
参考文献
MERCK and CO., INC.
Patent: WO2005/118529 A2, 2005 ;
Location in patent: Page/Page column 32 ;
