a-羟基-[1,1-联苯]-4-乙酸合成路线 （共 16 条）
反应条件
phosphorus; iodine; acetic acid
参考文献
Blicke; Grier
Journal of the American Chemical Society, 1943 , vol. 65, p. 1725,1727
反应条件
Najera palladacycle I; tetra(n-butyl)ammonium hydroxide; potassium carbonate; [(t-Bu)3PH]BF4 in N,N-dimethyl-formamide
T=130°C; Suzuki-Miyaura coupling; 0.333333 h; Microwave irradiation;
参考文献
Alonso, Diego A.; Civicos; Najera, Carmen
Synlett, 2009 , # 18 p. 3011 - 3015
反应条件
sodium carbonate; Pd-complex on fluorous reversed silica gel in water
T=80°C; Suzuki reaction; 16 h;
参考文献
Tzschucke, Carl Christoph; Bannwarth, Willi
Helvetica Chimica Acta, 2004 , vol. 87, # 11 p. 2882 - 2889
参考文献
The Ohio State University Research Foundation
Patent: US5399721 A1, 1995 ;
参考文献
The Ohio State University Research Foundation
Patent: US5504108 A1, 1996 ;
反应条件
tin(IV) chloride
Erwaermen des Reaktionsprodukts mit wss. Kalilauge und anschliessend mit wss. Salzsaeure;
参考文献
Riebsomer et al.
Journal of the American Chemical Society, 1942 , vol. 64, p. 2080
反应条件
ethanol; platinum palladium-catalyst
Hydrogenation.Behandlung des Reaktionsprodukts mit warmer aethanol. Kalilauge;
参考文献
Blicke; Grier
Journal of the American Chemical Society, 1943 , vol. 65, p. 1725,1727
反应条件
1: aluminium chloride; carbon disulfide
2: platinum palladium-catalyst; aqueous ethanol / Hydrogenation.Behandlung des Reaktionsprodukts mit warmer aethanol. Kalilauge
View Scheme
参考文献
Blicke; Grier
Journal of the American Chemical Society, 1943 , vol. 65, p. 1725,1727
反应条件
2,3,5-triphenyl-2H-tetrazolium chloride; N-benzyl-trimethylammonium hydroxide in methanol; dichloromethane
参考文献
Moehrle; Schittenhelm
Archiv der Pharmazie, 1972 , vol. 305, # 4 p. 309 - 314
反应条件
1: aq. H2SO4 / methanol
2: 2,3,5-triphenyl-tetrazolium chloride, <PhCH2NMe3>OH / methanol; CH2Cl2
View Scheme
参考文献
Moehrle; Schittenhelm
Archiv der Pharmazie, 1972 , vol. 305, # 4 p. 309 - 314
