2-甲氧基-4-(三氟甲基)苯甲酸合成路线

10049-21-5磷酸二氢钠单水合物+132927-09-42-甲氧基-4-(三氟甲氧)苯甲醛→448-36-22-甲氧基-4-(三氟甲基)苯甲酸

参考文献

Eisai Co., Ltd.
Patent: EP1216980 A1, 2002 ;
EP 1216980 A1

286441-66-52-甲氧基-4-三氟甲基苯甲酸甲酯→448-36-22-甲氧基-4-(三氟甲基)苯甲酸

参考文献

Lynch, John K.; Freeman, Jennifer C.; Judd, Andrew S.; Iyengar, Rajesh; Mulhern, Mathew; Zhao, Gang; Napier, James J.; Wodka, Dariusz; Brodjian, Sevan; Dayton, Brian D.; Falls, Doug; Ogiela, Christopher; Reilly, Regina M.; Campbell, Thomas J.; Polakowski, James S.; Hernandez, Lisa; Marsh, Kennan C.; Shapiro, Robin; Knourek-Segel, Victoria; Droz, Brian; Bush, Eugene; Brune, Michael; Preusser, Lee C.; Fryer, Ryan M.; Reinhart, Glenn A.; Houseman, Kathryn; Diaz, Gilbert; Mikhail, Ann; Limberis, James T.; Sham, Hing L.; Collins, Christine A.; Kym, Philip R.
Journal of Medicinal Chemistry, 2006 , vol. 49, # 22 p. 6569 - 6584

98-17-93-三氟甲基苯酚→448-36-22-甲氧基-4-(三氟甲基)苯甲酸

参考文献

McBee; Rapkin
Journal of the American Chemical Society, 1951 , vol. 73, p. 2375

585-43-3→448-36-22-甲氧基-4-(三氟甲基)苯甲酸

参考文献

McBee; Rapkin
Journal of the American Chemical Society, 1951 , vol. 73, p. 2375

585-49-9→448-36-22-甲氧基-4-(三氟甲基)苯甲酸

参考文献

McBee; Rapkin
Journal of the American Chemical Society, 1951 , vol. 73, p. 2375

402-07-32-溴-5-三氟甲基苯甲醚→448-36-22-甲氧基-4-(三氟甲基)苯甲酸

参考文献

McBee; Rapkin
Journal of the American Chemical Society, 1951 , vol. 73, p. 2375