1: C24H29N2O5Pol With trifluoroacetic acid in dichloromethane 0.5 h; solid phase reaction; 2: 1-(tert-butoxycarbonyl)-L-proline With benzotriazol-1-ol; O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate; N-ethyl-N,N-diisopropylamine in 1-methyl-pyrrolidin-2-one; dimethyl sulfoxide 3 h; solid phase reaction; 3: t-Boc-L-valine; (2S,3S)-2-(tert-butoxycarbonylamino)-3-methylpentanoic acid; boc-Ng-tosyl-L-arginine; (2S)-3-cyclohexyloxycarbonyl-2-t-butoxycarbonylaminopropanoic acid; Boc-L-tyrosine(2-Br-Z)-OH; N-Boc-L-His(Tos)-OH Further stages;

in water T=30°C; 0.55 h; Shimeji kininase enzyme, 0.01 M pH 7.4 phosphate buffer;

Multistep reaction;

Multistep reaction;

wheat carboxypeptidase from wheat bran T=30°C; pH 4.0; structure-reactivity relationship; Rate constant;

wheat carboxypeptidase from wheat bran T=30°C; pH 4.0; structure-reactivity relationship; Rate constant;