2-氯-4,6-二甲基嘧啶合成路线 （共 52 条）
反应条件
trichlorophosphate 10 h; Heating;
参考文献
Bhasin; Arora, Ekta; Grover, Alka S.; Jyoti; Singh; Mehta; Bhasin, Aman K.K.; Jacob
Journal of Organometallic Chemistry, 2013 , vol. 732, p. 137 - 141
反应条件
trichlorophosphate 1 h; Heating / reflux;
参考文献
TORAY INDUSTRIES, INC.
Patent: EP1840121 A1, 2007 ;
反应条件
in diethyl ether; trichlorophosphate
参考文献
Dupont Pharmaceuticals Company
Patent: US6107301 A1, 2000 ;
US 6107301 A
参考文献
Imperial Chemical Industries PLC
Patent: US5266570 A1, 1993 ;
反应条件
1: 2-mercapto-4,6-dimethyl-pyrimidine With hydrogenchloride; sodium hypochlorite in dichloromethane; water T=-10 - -5°C; 0.25 h; 2: benzylamine in dichloromethane T=0°C; 0.5 h;
参考文献
Wright, Stephen W.; Hallstrom, Kelly N.
Journal of Organic Chemistry, 2006 , vol. 71, # 3 p. 1080 - 1084
反应条件
1: 75 percent / conc. HCl / ethanol / 24 h / Heating 2: 77 percent / phosphorus oxychloride / 10 h / Heating View Scheme
参考文献
Becker, Irwin
Journal of Heterocyclic Chemistry, 2004 , vol. 41, # 3 p. 343 - 348
反应条件
hydrogenchloride; sodium nitrite
参考文献
Wang, Bao-Lei; Shi, Yan-Xia; Ma, Yi; Liu, Xing-Hai; Li, Yong-Hong; Song, Hai-Bin; Li, Bao-Ju; Li, Zheng-Ming
Journal of Agricultural and Food Chemistry, 2010 , vol. 58, # 9 p. 5515 - 5522
反应条件
chloroform T=550 - 555°C; Further byproducts given. Title compound not separated from byproducts;
参考文献
Bhatti, Inayat A.; Busby, Reginald E.; Bin Mohamed, Murtedza; Parrick, John; Shaw, C. J. Granville
Journal of the Chemical Society - Perkin Transactions 1, 1997 , # 24 p. 3581 - 3585
反应条件
chloroform T=550 - 555°C; Further byproducts given. Title compound not separated from byproducts;
参考文献
Bhatti, Inayat A.; Busby, Reginald E.; Bin Mohamed, Murtedza; Parrick, John; Shaw, C. J. Granville
Journal of the Chemical Society - Perkin Transactions 1, 1997 , # 24 p. 3581 - 3585
反应条件
23 h; Heating / reflux;
参考文献
DuPont Pharmaceuticals Company
Patent: US6342503 B1, 2002 ;
Location in patent: Example 1 ;
US 6342503 B1
