反应条件
1: 1.) N-hydroxybenzotriazole (HOBt), N,N'-dicyclohexylcarbodiimide (DCC), 2.) Et3N / 1.) DMF, 0 deg C, 1 h, 2.) DMF, from 0 deg C, 1 h to RT, overnight
2: 100 percent / 1N aq. NaOH / methanol / 1 h / Ambient temperature
View Scheme
参考文献
Morier-Teissier; Boitte; Helbecque; Bernier; Pommery; Duvalet; Fournier; Hecquet; Catteau; Henichart
Journal of Medicinal Chemistry, 1993 , vol. 36, # 15 p. 2084 - 2090
