6-甲基-4-苯基-吡喃-2-酮合成路线 （共 18 条）
反应条件
bis-triphenylphosphine-palladium(II) chloride; potassium carbonate; p-toluenesulfonyl chloride in tetrahydrofuran; water
T=60°C;
参考文献
Hu, Yi; Ding, Qiuping; Ye, Shengqing; Peng, Yiyuan; Wu, Jie
Tetrahedron, 2011 , vol. 67, # 38 p. 7258 - 7262
反应条件
1: (Z)-3-iodo-3-phenyl-2-propenoic acid With tetrabutylammomium bromide; palladium diacetate; triphenylphosphine in N,N-dimethyl-formamide
T=20°C; 0.166667 h;
2: allenyl tributylstannane in N,N-dimethyl-formamide
4 h;
参考文献
Rousset; Abarbri; Thibonnet; Duchene; Parrain
Chemical Communications, 2000 , # 20 p. 1987 - 1988
反应条件
palladium diacetate; potassium fluoride; biphenyl-2-yl-di-tert-butyl-phosphane in tetrahydrofuran
T=25°C; Suzuki coupling;
参考文献
Fairlamb, Ian J. S.; Marrison, Lester R.; Dickinson, Julia M.; Lu, Feng-Ju; Schmidt, Jan Peter
Bioorganic and Medicinal Chemistry, 2004 , vol. 12, # 15 p. 4285 - 4299
反应条件
1,1'-bis-(diphenylphosphino)ferrocene; cesium fluoride in water; toluene
T=50°C; 12 h;
参考文献
Wu, Jie; Zhang, Liang; Gao, Ke
European Journal of Organic Chemistry, 2006 , # 23 p. 5260 - 5263
反应条件
sulfuric acid in dichloromethane
T=20°C; 0.5 h;
参考文献
Xu, Haiyun; Zhang, Xinying; He, Yan; Guo, Shenghai; Fan, Xuesen
Chemical Communications, 2012 , vol. 48, # 25 p. 3121 - 3123
反应条件
1,1'-bis-(diphenylphosphino)ferrocene; dipotassium hydrogenphosphate; RhCl(PPh3)3 in toluene
T=80°C; Suzuki-Miyaura cross-coupling reaction; 12 h;
参考文献
Wu, Jie; Zhang, Liang; Luo, Yong
Tetrahedron Letters, 2006 , vol. 47, # 38 p. 6747 - 6750
反应条件
palladium diacetate in tetrahydrofuran
T=20°C; Inert atmosphere;
参考文献
Gao, Wei; Luo, Yong; Ding, Qiuping; Peng, Yiyuan; Wu, Jie
Tetrahedron Letters, 2010 , vol. 51, # 1 p. 136 - 138
反应条件
potassium phosphate; CM-phos; palladium diacetate; triethylamine in tert-butyl alcohol
T=50°C; Suzuki coupling; 2 h; Inert atmosphere;
参考文献
Wong, Pui Yu; Chow, Wing Kin; Chung, Kin Ho; So, Chau Ming; Lau, Chak Po; Kwong, Fuk Yee
Chemical Communications, 2011 , vol. 47, # 29 p. 8328 - 8330
反应条件
sulfuric acid in acetonitrile
T=40°C; 2 h;
参考文献
Xu, Haiyun; Zhang, Xinying; He, Yan; Guo, Shenghai; Fan, Xuesen
Chemical Communications, 2012 , vol. 48, # 25 p. 3121 - 3123
反应条件
1: 29 percent / Bu4NBr; P2O5 / toluene / 1 h / 100 °C
2: 90 percent / K3PO4*H2O; SPhos / Pd(OAc)2 / tetrahydrofuran / 2 h / 20 °C
View Scheme
参考文献
Woo, Jacqueline C.S.; Walker, Shawn D.; Faul, Margaret M.
Tetrahedron Letters, 2007 , vol. 48, # 32 p. 5679 - 5682
