2-(4-甲基苯基)吡啶合成路线 （共 103 条）
反应条件
tetrakis(triphenylphosphine) palladium(0); hexamethyl-distannane; lithium chloride in 1,4-dioxane Heating;
参考文献
Hitchcock; Mayhugh; Gregory
Tetrahedron Letters, 1995 , vol. 36, # 50 p. 9085 - 9088
反应条件
1.1: n-BuLi / tetrahydrofuran; hexane / 16 h / 20 °C 1.2: 75 percent / isopropanol / tetrahydrofuran; hexane / 4 h / Heating 2.1: 10 percent / Pd(OAc)2; K2CO3; PPh3 / CuI / tetrahydrofuran / 100 °C View Scheme
参考文献
Tetrahedron Letters, , vol. 45, # 4 p. 685 - 687
反应条件
C67H55FeP4 in toluene T=100°C; Negishi coupling reaction; 4 h; Inert atmosphere; Kinetics; ConcentrationTime;
参考文献
Adams, Christopher J.; Bedford, Robin B.; Carter, Emma; Gower, Nicholas J.; Haddow, Mairi F.; Harvey, Jeremy N.; Huwe, Michael; Cartes, M. Angeles; Mansell, Stephen M.; Mendoza, Carla; Murphy, Damien M.; Neeve, Emily C.; Nunn, Joshua
Journal of the American Chemical Society, 2012 , vol. 134, # 25 p. 10333 - 10336
反应条件
tBu2P-N=P(iBuPCH2CH2)3N; tetrabutyl ammonium fluoride; palladium diacetate T=80°C; Hiyama coupling; 2 h; Inert atmosphereNeat (no solvent);
参考文献
Raders, Steven M.; Kingston, Jesudoss V.; Verkade, John G.
Journal of Organic Chemistry, 2010 , vol. 75, # 5 p. 1744 - 1747
反应条件
p-tolyl-lithium; toluene
参考文献
Journal of the American Chemical Society, , vol. 74, p. 2667
Canadian Journal of Chemistry, , vol. 31, p. 457,466
Journal of the Chemical Society, , p. 100,101
反应条件
1: 6 h / Irradiation 2: 1.3 mg / H2 / Pd on charcoal (10percent) / ethanol / 760 Torr / Ambient temperature View Scheme
参考文献
Chemical and Pharmaceutical Bulletin, , vol. 33, # 3 p. 1009 - 1015
反应条件
1: 5.4 mg / LiAlH4 / diethyl ether / Ambient temperature 2: 1.3 mg / H2 / Pd on charcoal (10percent) / ethanol / 760 Torr / Ambient temperature View Scheme
参考文献
Chemical and Pharmaceutical Bulletin, , vol. 33, # 3 p. 1009 - 1015
反应条件
1: 6 h / Irradiation 2: 1.3 mg / H2 / Pd on charcoal (10percent) / ethanol / 760 Torr / Ambient temperature View Scheme
参考文献
Chemical and Pharmaceutical Bulletin, , vol. 33, # 3 p. 1009 - 1015
反应条件
1.1: dichloromethane / 0.5 h / 20 °C / |Inert atmosphere 1.2: 0.25 h / 20 °C / |Inert atmosphere 2.1: triethylamine / tetrahydrofuran / 18 h / 0 - 20 °C / |Inert atmosphere 3.1: tetrakis(triphenylphosphine) palladium(0); potassium carbonate / ethanol / 18 h / 100 °C / |Inert atmosphere View Scheme
参考文献
Organic and Biomolecular Chemistry, , vol. 12, # 1 p. 47 - 52
反应条件
tetrakis(triphenylphosphine) palladium(0); tetrabutyl ammonium fluoride; silver(l) oxide in tetrahydrofuran; N,N-dimethyl-formamide T=90°C; 18 h;
参考文献
Tetrahedron Letters, , vol. 49, # 44 p. 6314 - 6315
