1,3-[2H,4H]-异喹啉二酮合成路线 （共 38 条）
反应条件
ammonium hydroxide in water 8 h; Ambient temperature;
参考文献
Wolfbeis, Otto S.; Trummer, Iris; Knierzinger, Andreas
Liebigs Annalen der Chemie, 1981 , # 5 p. 811 - 818
反应条件
in ammonium hydroxide
参考文献
Lee, Chih-Hung; Bayburt, Erol K.; DiDomenico, Stanley; Drizin, Irene; Gomtsyan, Arthur R.; Koenig, John R.; Perner, Richard J.; Schmidt, Robert G.; Turner, Sean C.; Jinkerson, Tammie K.; Zheng, Guo Zhu
Patent: US2005/113576 A1, 2005 ;
Location in patent: Page/Page column 29-30 ;
US 20050113576 A1
反应条件
anhydrous ammonium carbonate
参考文献
Farmitalia Carlo Erba S.r.L.
Patent: US5587385 A1, 1996 ;
US 5587385 A
反应条件
in ethylene glycol T=175°C; sealed tube;
参考文献
ALMIRALL, S.A.; VIDAL JUAN, Bernat; FORNS BERENGUEL, Maria Pilar; CASTILLO MCQUADE, Marcos; ERRA SOLA, Montserrat; MIR CEPEDA, Marta
Patent: WO2012/41476 A1, 2012 ;
Location in patent: Page/Page column 56-57 ;
WO 2012/041476 A1
反应条件
silica gel; molybdenum(VI) oxide in ethanol Beckmann rearrangement; Heating;
参考文献
Dongare, Mohan K.; Bhagwat, Vivekanand V.; Ramana; Gurjar, Mukund K.
Tetrahedron Letters, 2004 , vol. 45, # 24 p. 4759 - 4762
反应条件
hydrogenchloride in 1,4-dioxane 12 h; Heating;
参考文献
Huh, Dal Ho; Jeong, Ji Sang; Lee, Hee Bong; Ryu, Hoejin; Kim, Young Gyu
Tetrahedron, 2002 , vol. 58, # 50 p. 9925 - 9932
反应条件
acetone T=20°C; P=1050.11 Torr; 3 h;
参考文献
Vicente, Jose; Gonzalez-Herrero, Pablo; Frutos-Pedreno, Roberto; Chicote, Maria-Teresa; Jones, Peter G.; Bautista, Delia
Organometallics, 2011 , vol. 30, # 5 p. 1079 - 1093
反应条件
hydrogenchloride 2.5 h; Heating;
参考文献
Deady, Leslie W.; Quazi, Nurul H.
Journal of Heterocyclic Chemistry, 1994 , vol. 31, # 4 p. 793 - 796
反应条件
hydrogenchloride 1 h; Heating;
参考文献
Barnard, Ian F.; Elvidge, John A.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1983 , # 8 p. 1813 - 1818
反应条件
1: 84 percent / PPh3 / CH2Cl2 / 0.5 h / 0 °C 2: 81 percent / H2O / ethyl acetate / 0.2 h / 20 °C 3: 79 percent / aq. HCl / dioxane / 12 h / Heating View Scheme
参考文献
Huh, Dal Ho; Jeong, Ji Sang; Lee, Hee Bong; Ryu, Hoejin; Kim, Young Gyu
Tetrahedron, 2002 , vol. 58, # 50 p. 9925 - 9932
