4-氟-2-硝基苯甲醚合成路线

394-33-22-硝基-4-氟苯酚+74-88-4甲基碘→445-83-04-氟-2-硝基苯甲醚

参考文献

VERTEX PHARMACEUTICALS INCORPORATED; CLEVELAND, Thomas; MAKINGS, Lewis R.; HAMILTON, Matthew; GROOTENHUIS, Peter D.J.
Patent: WO2005/26137 A2, 2005 ;
Location in patent: Page/Page column 230-231 ;
WO 2005/026137 A2

459-60-94-氟苯甲醚→517-25-9三硝基甲烷+364-32-92,6-二硝基-4-氟苯酚+445-83-04-氟-2-硝基苯甲醚

参考文献

Sankararaman,S.; Haney,W.A.; Kochi,J.K.
Journal of the American Chemical Society, 1987 , vol. 109, p. 7824

459-60-94-氟苯甲醚→342-49-4+445-83-04-氟-2-硝基苯甲醚+110175-19-4

参考文献

Sankararaman,S.; Haney,W.A.; Kochi,J.K.
Journal of the American Chemical Society, 1987 , vol. 109, p. 7824

394-33-22-硝基-4-氟苯酚→445-83-04-氟-2-硝基苯甲醚

参考文献

Pfizer Inc.
Patent: US5071863 A1, 1991 ;
US 5071863 A

459-60-94-氟苯甲醚→445-83-04-氟-2-硝基苯甲醚

参考文献

Finger et al.
Journal of the American Chemical Society, 1959 , vol. 81, p. 94,95, 97

459-60-94-氟苯甲醚+509-14-8四硝基甲烷→342-49-4+445-83-04-氟-2-硝基苯甲醚+110175-19-4

参考文献

Sankararaman,S.; Haney,W.A.; Kochi,J.K.
Journal of the American Chemical Society, 1987 , vol. 109, p. 7824

459-60-94-氟苯甲醚→445-83-04-氟-2-硝基苯甲醚+123871-59-04-氟-4-硝基-2,5-环己二烯-1-酮

参考文献

Clewley, Robin G.; Fischer, Alfred; Henderson, George N.
Canadian Journal of Chemistry, 1989 , vol. 67, p. 1472 - 1479

459-60-94-氟苯甲醚→394-33-22-硝基-4-氟苯酚+445-83-04-氟-2-硝基苯甲醚

参考文献

Bloomfield, Colin; Manglik, Ajay K.; Moodie, Roy B.; Schofield, Kenneth; Tobin, Geoffrey D.
Journal of the Chemical Society, Perkin Transactions 2: Physical Organic Chemistry (1972-1999), 1983 , p. 75 - 82

459-60-94-氟苯甲醚→394-33-22-硝基-4-氟苯酚+445-83-04-氟-2-硝基苯甲醚+110175-19-4

参考文献

Butts, Craig P.; Eberson, Lennart; Hartshorn, Michael P.; Robinson, Ward T.
Journal of the Chemical Society, Perkin Transactions 2: Physical Organic Chemistry (1972-1999), 1996 , # 9 p. 1877 - 1888

186581-53-3重氮甲烷+394-33-22-硝基-4-氟苯酚→445-83-04-氟-2-硝基苯甲醚

参考文献

Zeegers, Petrus J.; Thompson, Malcolm J.
Magnetic Resonance in Chemistry, 1992 , vol. 30, # 6 p. 497 - 499