3-氨基-1,1-联苯-4-羧酸合成路线 （共 7 条）
反应条件
sodium hydroxide; dihydrogen peroxide
T=50°C; 0.5 h;
参考文献
Gerard, Anne-Laure; Lisowski, Vincent; Rault, Sylvain
Tetrahedron, 2005 , vol. 61, # 25 p. 6082 - 6087
反应条件
1: 71 percent / Pd(PPh3)4; aq. NaHCO3 / 1,2-dimethoxy-ethane / Heating
2: 54 percent / aq. NaOH; aq. H2O2 / 0.5 h / 50 °C
View Scheme
参考文献
Gerard, Anne-Laure; Lisowski, Vincent; Rault, Sylvain
Tetrahedron, 2005 , vol. 61, # 25 p. 6082 - 6087
反应条件
1: 20 percent / H2SO4
2: 71 percent / Pd(PPh3)4; aq. NaHCO3 / 1,2-dimethoxy-ethane / Heating
3: 54 percent / aq. NaOH; aq. H2O2 / 0.5 h / 50 °C
View Scheme
参考文献
Gerard, Anne-Laure; Lisowski, Vincent; Rault, Sylvain
Tetrahedron, 2005 , vol. 61, # 25 p. 6082 - 6087
反应条件
1: 90 percent / NH2OH*HCl; aq. HCl; Na2SO4
2: 20 percent / H2SO4
3: 71 percent / Pd(PPh3)4; aq. NaHCO3 / 1,2-dimethoxy-ethane / Heating
4: 54 percent / aq. NaOH; aq. H2O2 / 0.5 h / 50 °C
View Scheme
参考文献
Gerard, Anne-Laure; Lisowski, Vincent; Rault, Sylvain
Tetrahedron, 2005 , vol. 61, # 25 p. 6082 - 6087
反应条件
sodium hydroxide; tetrakis(triphenylphosphine) palladium(0); sodium carbonate
1.) toluene, reflux, 6 h, 2.) MeOH; Yield given. Multistep reaction;
参考文献
Quan; Wityak; Dominguez; Duncia; Kettner; Ellis; Liauw; Park; Santella; Knabb; Thoolen; Weber; Wexler
Bioorganic and Medicinal Chemistry Letters, 1997 , vol. 7, # 13 p. 1595 - 1600
反应条件
ethanol; nickel
Hydrogenation;
参考文献
Sues; Moeller
Justus Liebigs Annalen der Chemie, 1955 , vol. 593, p. 91,109
反应条件
1: H2SO4; aqueous acetic acid
2: Raney nickel; ethanol / Hydrogenation
View Scheme
参考文献
Sues; Moeller
Justus Liebigs Annalen der Chemie, 1955 , vol. 593, p. 91,109
