4,4-二甲基-5-亚甲基-1,3-二氧戊环-2-酮合成路线 （共 17 条）
反应条件
silver trifluoroacetate; triphenylphosphine; palladium diacetate in N,N-dimethyl-formamide T=100°C; Arylation; 20 h;
参考文献
Toullec, Patrick; Carbayo Martin, Aranzazu; Gio-Batta, Monica; Bruneau, Christian; Dixneuf, Pierre H.
Tetrahedron Letters, 2000 , vol. 41, # 29 p. 5527 - 5531
反应条件
1: 95 percent / ammonia / ethyl acetate / Ambient temperature 2: 86 percent / p-toluenesulfonic cid / CH2Cl2 / 18 h / Heating View Scheme
参考文献
Le Gendre, Pierre; Thominot, Patrice; Bruneau, Christian; Dixneuf, Pierre H.
Journal of Organic Chemistry, 1998 , vol. 63, # 6 p. 1806 - 1809
反应条件
T=110°C; 9 h; Product distribution; Further Variations:Temperaturestime;
参考文献
Chemistry of Heterocyclic Compounds, , vol. 40, # 8 p. 992 - 1001
反应条件
1: 47 percent / ZnCl2 / xylene / 12 h / Heating 2: 29 percent / ZnCl2 / paraffin / 8 h / 200 - 210 °C View Scheme
参考文献
Laas, Harald; Nissen, Axel; Nuerrenbach, Axel
Synthesis, 1981 , # 12 p. 958 - 959
反应条件
lithium chloride; zinc(II) chloride in paraffin 1.) 10 h, 190 degC, 2.) 6 h, 200 - 205 degC;
参考文献
Laas, Harald; Nissen, Axel; Nuerrenbach, Axel
Synthesis, 1981 , # 12 p. 958 - 959
反应条件
1: 74 percent / ZnCl2 / xylene / 12 h / Heating 2: 63 percent / ZnCl2 / paraffin / 8 h / 200 - 210 °C View Scheme
参考文献
Laas, Harald; Nissen, Axel; Nuerrenbach, Axel
Synthesis, 1981 , # 12 p. 958 - 959
反应条件
tributylphosphine
T=100°C; P=75006 Torr; 15 h;
参考文献
Kayaki, Yoshihito; Yamamoto, Masafumi; Ikariya, Takao
Journal of Organic Chemistry, 2007 , vol. 72, # 2 p. 647 - 649
反应条件
1,3-bis(tert-butyl)-imidazolium-2-carboxylate
T=50°C; P=760.051 Torr; Inert atmosphere;
参考文献
Kayaki, Yoshihito; Yamamoto, Masafumi; Ikariya, Takao
Angewandte Chemie, International Edition, 2009 , vol. 48, # 23 p. 4194 - 4197
反应条件
copper(l) chloride; [bmim][BS]
T=120°C; P=7600 Torr; 8 h;
参考文献
Gu, Yanlong; Shi, Feng; Deng, Youquan
Journal of Organic Chemistry, 2004 , vol. 69, # 2 p. 391 - 394
反应条件
carbon dioxide; tetraethylammonium chloride; silver(I) acetate; triphenylphosphine
参考文献
Roche Vitamins Inc.
Patent: US5817838 A1, 1998 ;
