(S)-(-)-2,2′,6,6′-四甲氧基-4,4′-双(二(3,5-二甲苯基)膦-3,3′-联吡啶合成路线 （共 5 条）
反应条件
1.1: LDA / tetrahydrofuran / -78 °C 1.2: 56 percent / tetrahydrofuran / -78 °C 2.1: 99 percent / H2O2 / acetone / 0 °C 3.1: Cu / dimethylformamide / 140 °C 3.2: (-)-L-DBTA / resolution of racemate 4.1: HSiCl3; Et3N View Scheme
参考文献
Wu, Jing; Chen, Hua; Kwok, Wai Him; Lam, Kim Hung; Zhou, Zhong Yuan; Yeung, Chi Hung; Chan, Albert S.C
Tetrahedron Letters, 2002 , vol. 43, # 8 p. 1539 - 1543
反应条件
1.1: LDA / tetrahydrofuran / -78 °C 1.2: 56 percent / tetrahydrofuran / -78 °C 2.1: 99 percent / H2O2 / acetone / 0 °C 3.1: Cu / dimethylformamide / 140 °C 3.2: (-)-L-DBTA / resolution of racemate 4.1: HSiCl3; Et3N View Scheme
参考文献
Wu, Jing; Chen, Hua; Kwok, Wai Him; Lam, Kim Hung; Zhou, Zhong Yuan; Yeung, Chi Hung; Chan, Albert S.C
Tetrahedron Letters, 2002 , vol. 43, # 8 p. 1539 - 1543
反应条件
1.1: LDA / tetrahydrofuran / -78 °C 1.2: 56 percent / tetrahydrofuran / -78 °C 2.1: 99 percent / H2O2 / acetone / 0 °C 3.1: Cu / dimethylformamide / 140 °C 3.2: (-)-L-DBTA / resolution of racemate 4.1: HSiCl3; Et3N View Scheme
参考文献
Wu, Jing; Chen, Hua; Kwok, Wai Him; Lam, Kim Hung; Zhou, Zhong Yuan; Yeung, Chi Hung; Chan, Albert S.C
Tetrahedron Letters, 2002 , vol. 43, # 8 p. 1539 - 1543
反应条件
1.1: 99 percent / H2O2 / acetone / 0 °C 2.1: Cu / dimethylformamide / 140 °C 2.2: (-)-L-DBTA / resolution of racemate 3.1: HSiCl3; Et3N View Scheme
参考文献
Wu, Jing; Chen, Hua; Kwok, Wai Him; Lam, Kim Hung; Zhou, Zhong Yuan; Yeung, Chi Hung; Chan, Albert S.C
Tetrahedron Letters, 2002 , vol. 43, # 8 p. 1539 - 1543
反应条件
1.1: Cu / dimethylformamide / 140 °C 1.2: (-)-L-DBTA / resolution of racemate 2.1: HSiCl3; Et3N View Scheme
参考文献
Wu, Jing; Chen, Hua; Kwok, Wai Him; Lam, Kim Hung; Zhou, Zhong Yuan; Yeung, Chi Hung; Chan, Albert S.C
Tetrahedron Letters, 2002 , vol. 43, # 8 p. 1539 - 1543
