1-叔丁基-1H-吡唑-5-胺合成路线 （共 3 条）
反应条件
potassium phosphate; tris(dibenzylideneacetone)dipalladium(0) chloroform complex; 9,9-dimethyl-4,5-bis(diphenyl-phosphino)xanthene in 1,4-dioxane T=100°C;
参考文献
Iwasawa, Yoshikuzu; Kato, Tetsuya; Kawanishi, Nobuhiko; Masutani, Kouta; Mita, Takashi; Nonoshita, Katsumasa; Ohkubo, Mitsuru
Patent: US2008/58347 A1, 2008 ;
Location in patent: Page/Page column 42 ;
US 20080058347 A1
反应条件
1: With sodium acetate in ethanol
T=20 - 80°C; 12 h;
2: With sodium hydrogencarbonate
参考文献
Iwasawa, Yoshikuzu; Kato, Tetsuya; Kawanishi, Nobuhiko; Masutani, Kouta; Mita, Takashi; Nonoshita, Katsumasa; Ohkubo, Mitsuru
Patent: US2008/58347 A1, 2008 ;
Location in patent: Page/Page column 63 ;
US 20080058347 A1
反应条件
sodium carbonate; potassium carbonate in water
T=20°C; regioselective reaction;
参考文献
Ji, Nan; Meredith, Erik; Liu, Donglei; Adams, Christopher M.; Artman III, Gerald D.; Jendza, Keith C.; Ma, Fupeng; Mainolfi, Nello; Powers, James J.; Zhang, Chun
Tetrahedron Letters, 2010 , vol. 51, # 52 p. 6799 - 6801
