1,3,4,5-四氢-2H-1-苯并氮杂卓-2-酮合成路线 （共 62 条）
反应条件
1: 80 percent / 6 M aq. HCl / 3.5 h / Heating
2: 99 percent / aq. HCl, NaOAc / 0.25 h
3: 70 percent / 98percent conc. H2SO4, NaN3 / benzene / 5 h / 65 °C
4: 91 percent / 6 M aq. HCl / 12 h / Heating
View Scheme
参考文献
Nicholls, Ian A.; Alewood, Paul F.; Brinkworth, Ross I.; Morrison, Stuart F.; Andrews, Peter R.
Journal of Chemical Research, Miniprint, 1993 , # 10 p. 2811 - 2826
反应条件
1: 68 percent / lithium aluminum hydride / tetrahydrofuran
2: 95 percent / HNO3; H2SO4
3: H2NNH2 / Pd/C / ethanol
View Scheme
参考文献
Johnson, Paul D.; Aristoff, Paul A.; Zurenko, Gary E.; Schaadt, Ronda D.; Yagi, Betty H.; Ford, Charles W.; Hamel, Judith C.; Stapert, Douglas; Moerman, Judy K.
Bioorganic and Medicinal Chemistry Letters, 2003 , vol. 13, # 23 p. 4197 - 4200
