1,3,4,5-四氢-2H-1-苯并氮杂卓-2-酮合成路线 （共 62 条）
反应条件
2,4,6-trichloro-1,3,5-triazine; C2F6NO4S2(1-)*C8H14N3O(1+) in acetonitrile T=20°C; Beckmann rearrangement; 7.5 h;
参考文献
Hullio, Ahmed Ali; Mastoi
Chinese Journal of Chemistry, 2012 , vol. 30, # 7 p. 1647 - 1657
反应条件
hydrogenchloride; sodium azide 4 h;
参考文献
Grunewald; Dahanukar
Journal of Heterocyclic Chemistry, 1994 , vol. 31, # 6 p. 1609 - 1617
反应条件
1: With AlCl3, aluminium chloride in dichloromethane T=-40 - 20°C; Beckmann rearrangement; 1.16667 h; 2: With water
参考文献
Lopez, Laura; Selent, Jana; Ortega, Raquel; Masaguer, Christian F.; Dominguez, Eduardo; Areias, Filipe; Brea, Jose; Loza, Maria Isabel; Sanz, Ferran; Pastor, Manuel
ChemMedChem, 2010 , vol. 5, # 8 p. 1300 - 1317
反应条件
methanol; trimethylsilyl iodide T=-15°C; 0.0166667 h;
参考文献
Zheng, Nan; Armstrong III, Joseph D.; Eng, Kan K.; Keller, Jennifer; Liu, Tom; Purick, Robert; Lynch, Joseph; Hartner, Frederick W.; Volante
Tetrahedron Asymmetry, 2003 , vol. 14, # 22 p. 3435 - 3446
反应条件
T=180°C; 6 h; Yield given;
参考文献
Ito, Yoshihiko; Kobayashi, Kazuhiro; Maeno, Masayuki; Saegusa, Takeo
Chemistry Letters, 1980 , p. 487 - 490
参考文献
Schroeter et al.
Chemische Berichte, 1930 , vol. 63, p. 1308,1325
反应条件
sodium azide; sulfuric acid; acetic acid
参考文献
Huisgen; Ugi
Justus Liebigs Annalen der Chemie, 1957 , vol. 610, p. 57,64
反应条件
PPa T=120°C; 2.5 h; other time, temperature; Product distribution;
参考文献
Potapov, V.M.; Dem'yanovich, V. M.; Vendrova, O. E.; Khlebnikov, V. A.
Chemistry of Heterocyclic Compounds (New York, NY, United States), 1983 , vol. 19, # 5 p. 528 - 533
Khimiya Geterotsiklicheskikh Soedinenii, 1983 , vol. 19, # 5 p. 655 - 660
反应条件
trimethylsilyl iodide; N,N,N',N,-tetramethylethylenediamine; iodine in dichloromethane
参考文献
Stein, Philip D.; O'Connor, Stephen P.; Shi, Yan; Li, Chi
Patent: US2002/25957 A1, 2002 ;
反应条件
1: 95 percent / TMSCl, NaI, I2, TMEDA / acetonitrile / -15 °C 2: 95 percent / NaN3 / dimethylformamide / 8 h / 25 °C 3: 1.) KOtBu; 2.) sat. NH4Cl 4: DMAP 5: H2 / (R)-BINAP RuCl2 / methanol / 60 °C / 2068.6 Torr View Scheme
参考文献
Armstrong, Joseph D. III; Eng, Kan K.; Keller, Jennifer L.; Purick, Robert M.; Hartner, Frederick W. Jr.; et al.
Tetrahedron Letters, 1994 , vol. 35, # 20 p. 3239 - 3242
