7-[(叔丁氧基)羰基]-7-氮杂双环[2.2.1]庚烷-1-羧酸合成路线 （共 5 条）
反应条件
hydrogen; palladium on activated charcoal in methanol
T=20°C; 3 h;
参考文献
Avenoza, Alberto; Busto, Jesus H.; Peregrina, Jesus M.; Rodriguez, Fernando
Journal of Organic Chemistry, 2002 , vol. 67, # 12 p. 4241 - 4249
反应条件
1: 7-tert-butoxycarbonyl-7-azabicyclolt;2.2.1gt;heptane With N,N,N',N,-tetramethylethylenediamine; sec.-butyllithium in diethyl ether; cyclohexane
T=0°C;
2: carbon dioxide in diethyl ether; cyclohexane
参考文献
Xiong, Hui; Frietze, William; Andisik, Donald W.; Ernst, Glen E.; Palmer, William E.; Hinkley, Lindsay; Varnes, Jeffrey G.; Albert, Jeffrey S.; Veale, Chris A.
Tetrahedron Letters, 2010 , vol. 51, # 51 p. 6741 - 6744
反应条件
jones reagent in acetone
T=0°C; Jones oxidation reaction; 4 h;
参考文献
Avenoza, Alberto; Busto, Jesus H; Cativiela, Carlos; Dordal, Albert; Frigola, Jordi; Peregrina, Jesus M
Tetrahedron, 2002 , vol. 58, # 22 p. 4505 - 4511
反应条件
1: 99 percent / LiAlH4 / tetrahydrofuran / 16 h / Heating
2: 98 percent / Pd(OH)2/C / methanol / 16 h
3: Jones reagent / acetone / 4 h / 0 °C
View Scheme
参考文献
Avenoza, Alberto; Busto, Jesus H; Cativiela, Carlos; Dordal, Albert; Frigola, Jordi; Peregrina, Jesus M
Tetrahedron, 2002 , vol. 58, # 22 p. 4505 - 4511
反应条件
1: 98 percent / Pd(OH)2/C / methanol / 16 h
2: Jones reagent / acetone / 4 h / 0 °C
View Scheme
参考文献
Avenoza, Alberto; Busto, Jesus H; Cativiela, Carlos; Dordal, Albert; Frigola, Jordi; Peregrina, Jesus M
Tetrahedron, 2002 , vol. 58, # 22 p. 4505 - 4511
