2-甲基-1,3-二氧戊环-2-丙酸合成路线 （共 13 条）
反应条件
1: 85 percent / pyridine / diethyl ether / Heating 2: 38 percent / i-Pr2NLi / diethyl ether / -60 °C View Scheme
参考文献
Moreau, J.-L.; Couffignal, R.; Arous-Chtara, R.
Tetrahedron, 1981 , vol. 37, p. 307 - 310
参考文献
Warren; Weedon
Journal of the Chemical Society, 1958 , p. 3972,3978
反应条件
1: 50.8 percent / LiAlH4 / diethyl ether / 0.5 h / 0 °C 2: 78 percent / LiBr, TMSCl / acetonitrile / 15 h / Heating View Scheme
参考文献
Joubert; Beney; Marsura; Luu-Duc
Journal of Labelled Compounds and Radiopharmaceuticals, 1995 , vol. 36, # 8 p. 745 - 754
反应条件
1: 85 percent / pyridine / diethyl ether / Heating 2: 85 percent / NaOH / H2O; methanol / 6 h / Heating View Scheme
参考文献
Journal of Organometallic Chemistry, , vol. 294, p. 139 - 144
反应条件
1: 85 percent / pyridine / diethyl ether / Heating 2: 38 percent / i-Pr2NLi / diethyl ether / -60 °C 3: 70 percent / H2SO4 / H2O; acetone / 4 h / 40 - 45 °C View Scheme
参考文献
Moreau, J.-L.; Couffignal, R.; Arous-Chtara, R.
Tetrahedron, 1981 , vol. 37, p. 307 - 310
反应条件
1: 85 percent / pyridine / diethyl ether / Heating 2: 60 percent / i-Pr2NLi / diethyl ether / -60 °C View Scheme
参考文献
Moreau, Jean-Louis; Couffignal, Renee
Journal of Organometallic Chemistry, 1985 , vol. 294, p. 139 - 144
反应条件
1: 85 percent / pyridine / diethyl ether / Heating 2: 60 percent / i-Pr2NLi / diethyl ether / -60 °C 3: 82 percent / H2SO4 / H2O; acetone / 4 h / 40 - 45 °C View Scheme
参考文献
Moreau, Jean-Louis; Couffignal, Renee
Journal of Organometallic Chemistry, 1985 , vol. 294, p. 139 - 144
反应条件
1: 85 percent / pyridine / diethyl ether / Heating
2: 70 percent / i-Pr2NLi / diethyl ether / -60 °C
3: 68 percent / H2SO4 / H2O; acetone / 4 h / 40 - 45 °C
View Scheme
参考文献
Moreau, Jean Louis; Couffignal, Rene
Tetrahedron Letters, 1982 , vol. 23, # 50 p. 5271 - 5274
反应条件
1: 50.8 percent / LiAlH4 / diethyl ether / 0.5 h / 0 °C
2: 78 percent / LiBr, TMSCl / acetonitrile / 15 h / Heating
3: 96 percent / p-TsOH / benzene / 5 h / Heating
View Scheme
参考文献
Joubert; Beney; Marsura; Luu-Duc
Journal of Labelled Compounds and Radiopharmaceuticals, 1995 , vol. 36, # 8 p. 745 - 754
反应条件
1: 85 percent / pyridine / diethyl ether / Heating
2: 47 percent / i-Pr2NLi / diethyl ether / -60 °C
3: 88 percent / H2SO4 / H2O; acetone / 4 h / 40 - 45 °C
View Scheme
参考文献
Moreau, Jean-Louis; Couffignal, Renee
Journal of Organometallic Chemistry, 1985 , vol. 294, p. 139 - 144
