5-苄氧基吲哚-3-乙酸合成路线 （共 15 条）
反应条件
1: in ethanol; water T=26 - 100°C; 60 h; 2: With hydrogenchloride; water pH=2;
参考文献
HERCULES TECHNOLOGY MANAGEMENT CO V, INC.; BLAGG, Julian
Patent: WO2011/47156 A1, 2011 ;
Location in patent: Page/Page column 45 ;
WO 2011/047156 A1
反应条件
1: diethyl ether / 0.33 h / 0 °C 2: sat. aq. NaHCO3 / diethyl ether / 0.5 h / Heating 3: methanol / 8 h / Heating 4: NaBH4 / tetrahydrofuran / 10 h / Heating View Scheme
参考文献
Ek; Witkop
Journal of the American Chemical Society, 1954 , vol. 76, p. 5579,5584
参考文献
Morales-Rios, Martha S.; Santos-Sanchez, Norma F.; Suarez-Castillo, Oscar R.; Joseph-Nathan, Pedro
Journal of Organic Chemistry, 2003 , vol. 68, # 2 p. 305 - 311
反应条件
ethanol; sodium cyanide
参考文献
Koo et al.
Journal of Organic Chemistry, 1959 , vol. 24, p. 179,183
Full Text Show Details
Ek; Witkop
Journal of the American Chemical Society, 1954 , vol. 76, p. 5579,5584
Full Text Show Details
Hamlin; Fischer
Journal of the American Chemical Society, 1951 , vol. 73, p. 5007
反应条件
1: ethanol; acetic acid 2: acetic acid; dioxane 3: NaCN; aqueous ethanol View Scheme
参考文献
Ek; Witkop
Journal of the American Chemical Society, 1954 , vol. 76, p. 5579,5584
反应条件
1: sat. aq. NaHCO3 / diethyl ether / 0.5 h / Heating 2: methanol / 8 h / Heating 3: NaBH4 / tetrahydrofuran / 10 h / Heating View Scheme
参考文献
Guan, Xiangming; Borchardt, Ronald T.
Tetrahedron Letters, 1994 , vol. 35, # 19 p. 3013 - 3016
反应条件
1: methanol / 8 h / Heating 2: NaBH4 / tetrahydrofuran / 10 h / Heating View Scheme
参考文献
Guan, Xiangming; Borchardt, Ronald T.
Tetrahedron Letters, 1994 , vol. 35, # 19 p. 3013 - 3016
反应条件
1: copper-powder; quinaldine / 245 - 250 °C 2: acetic acid; ethanol 3: CH3I / Erwaermen des erhaltenen Methojodids mit NaCN in H2O 4: aq.-ethanolic KOH View Scheme
参考文献
Stoll et al.
Helvetica Chimica Acta, 1955 , vol. 38, p. 1452,1469
反应条件
1: CH3I / Erwaermen des erhaltenen Methojodids mit NaCN in H2O 2: aq.-ethanolic KOH View Scheme
参考文献
Stoll et al.
Helvetica Chimica Acta, 1955 , vol. 38, p. 1452,1469
反应条件
1: Na2S2O4; aqueous NaOH 2: copper-powder; quinaldine / 245 - 250 °C 3: acetic acid; ethanol 4: CH3I / Erwaermen des erhaltenen Methojodids mit NaCN in H2O 5: aq.-ethanolic KOH View Scheme
参考文献
Stoll et al.
Helvetica Chimica Acta, 1955 , vol. 38, p. 1452,1469
