C-[2,2-二硫代苯-5-基甲基]胺合成路线 （共 5 条）
反应条件
water; triphenylphosphine in tetrahydrofuran
参考文献
MERCK and CO., INC.
Patent: WO2003/101381 A2, 2003 ;
Location in patent: Page 50 ;
WO 03/101381 A2
反应条件
ethylenediamine in 1,4-dioxane; propan-1-ol; water 24 h; Reflux;
参考文献
Murai, Norio; Miyano, Masayuki; Yonaga, Masahiro; Tanaka, Keigo
Organic Letters, 2012 , vol. 14, # 11 p. 2818 - 2821
反应条件
1: dicyclohexyl(2′,6′-dimethoxybiphenyl-2-yl)phosphine; sodium carbonate; bis(dibenzylideneacetone)-palladium(0) / 1,4-dioxane; water / 36 h / Reflux 2: ethylenediamine / 1,4-dioxane; propan-1-ol; water / 24 h / Reflux View Scheme
参考文献
Murai, Norio; Miyano, Masayuki; Yonaga, Masahiro; Tanaka, Keigo
Organic Letters, 2012 , vol. 14, # 11 p. 2818 - 2821
反应条件
1.1: n-BuLi / tetrahydrofuran / -78 °C 1.2: 76 percent / tetrahydrofuran 2.1: Zn(N3)2*Py; DPPA; DBU / CH2Cl2 / 20 °C 3.1: PPh3; H2O / tetrahydrofuran View Scheme
参考文献
Shao, Pengchang P.; Ok, Dong; Fisher, Michael H.; Garcia, Maria L.; Kaczorowski, Gregory J.; Li, Chunshi; Lyons, Kathryn A.; Martin, William J.; Meinke, Peter T.; Priest, Birgit T.; Smith, McHardy M.; Wyvratt, Matthew J.; Ye, Feng; Parsons, William H.
Bioorganic and Medicinal Chemistry Letters, 2005 , vol. 15, # 7 p. 1901 - 1907
反应条件
1: Zn(N3)2*Py; DPPA; DBU / CH2Cl2 / 20 °C 2: PPh3; H2O / tetrahydrofuran View Scheme
参考文献
Shao, Pengchang P.; Ok, Dong; Fisher, Michael H.; Garcia, Maria L.; Kaczorowski, Gregory J.; Li, Chunshi; Lyons, Kathryn A.; Martin, William J.; Meinke, Peter T.; Priest, Birgit T.; Smith, McHardy M.; Wyvratt, Matthew J.; Ye, Feng; Parsons, William H.
Bioorganic and Medicinal Chemistry Letters, 2005 , vol. 15, # 7 p. 1901 - 1907
