5,8,8a,9-四氢-9-羟基-5-(3,4,5-三甲氧基苯基)-(5R,5aR,8aR,9S)-呋喃并[3',4':6,7]萘并[2,3-d]-1,3-二氧杂环戊烯-6(5aH)-酮合成路线 （共 4 条）
4375-07-95,8,8a,9-四氢-9-羟基-5-(3,4,5-三甲氧基苯基)-(5R,5aR,8aR,9S)-呋喃并[3',4':6,7]萘并[2,3-d]-1,3-二氧杂环戊烯-6(5aH)-酮
→
反应条件
1: ethanol; sodium acetate 2: acetone; aqueous hydrochloric acid View Scheme
参考文献
Hartwell; Schrecker
Journal of the American Chemical Society, 1951 , vol. 73, p. 2909,2916
4375-07-95,8,8a,9-四氢-9-羟基-5-(3,4,5-三甲氧基苯基)-(5R,5aR,8aR,9S)-呋喃并[3',4':6,7]萘并[2,3-d]-1,3-二氧杂环戊烯-6(5aH)-酮
→
参考文献
Schrecker; Hartwell
Journal of the American Chemical Society, 1954 , vol. 76, p. 752
4375-07-95,8,8a,9-四氢-9-羟基-5-(3,4,5-三甲氧基苯基)-(5R,5aR,8aR,9S)-呋喃并[3',4':6,7]萘并[2,3-d]-1,3-二氧杂环戊烯-6(5aH)-酮
→
反应条件
water; boron trichloride; barium carbonate 1.) CH2Cl2, -20 deg C, 0.5 h, 2.) acetone, reflux, 2 h; Yield given. Multistep reaction;
参考文献
Terada; Fujimoto; Nomura; Yamashita; Kobunai; Takeda; Wierzba; Yamada; Yamaguchi
Chemical and Pharmaceutical Bulletin, 1992 , vol. 40, # 10 p. 2720 - 2727
4375-07-95,8,8a,9-四氢-9-羟基-5-(3,4,5-三甲氧基苯基)-(5R,5aR,8aR,9S)-呋喃并[3',4':6,7]萘并[2,3-d]-1,3-二氧杂环戊烯-6(5aH)-酮
→
参考文献
Hartwell; Schrecker
Journal of the American Chemical Society, 1951 , vol. 73, p. 2909,2916
