copper(I) oxide in acetonitrile T=65°C; 1.5 h;

1: thionyl chloride / 24 h / Ambient temperature 2: 31 percent / Et3N / CH2Cl2 / 0.5 h / Ambient temperature View Scheme

esterase from Sulfolobus tokodaii strain 7 in acetonitrile T=70°C; pH=7; Enzymatic reaction;

arylmalonate decarboxylase-G74C/C188G Enzymatic reaction; optical yield given as percent eeenantioselective reaction;

esterase from Sulfolobus tokodaii strain 7 in acetonitrile T=70°C; pH=7; Enzymatic reaction;

DAHP; manganese sulphate; dipotassium hydrogenphosphate; Phenylmalonic acid; water; magnesium sulfate; iron(II) sulfate; anhydrous zinc sulfate; peptone; yeast extract; 5-[(3AS,4S,6AR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl]pentanoic acid T=30°C; 120 h; other α-methyl-α-arylmalonic acids; enzyme-mediated asymmetric decarboxylation of disubstituted malonic acids, absolute configurations of products; Product distribution;

esterase from Sulfolobus tokodaii strain 7 in acetonitrile T=70°C; pH=7; Enzymatic reaction;

sodium hydroxide in ethanol 24 h; Ambient temperature;

1: 74 percent / Na / ethanol / 1 h / Ambient temperature 2: 52 percent / aq. NaOH / ethanol / 24 h / Ambient temperature View Scheme

potassium hydroxide in ethanol Ambient temperature;