5-氨基-3-苯基异噁唑合成路线 （共 33 条）
反应条件
1: 44 percent / Na2CO3 / CHCl3 / 7 h / Heating
2: 74 percent / ethanol / 30 h / Heating
View Scheme
参考文献
Tatee; Kurashige; Shiozawa; Narita; Takei; Ito; Miyazaki; Yamanaka; Mizugaki; Sakamoto
Chemical and Pharmaceutical Bulletin, 1986 , vol. 34, # 4 p. 1634 - 1642
反应条件
sodium amide; benzene
16 h; Heating;
参考文献
Tatee; Kurashige; Shiozawa; Narita; Takei; Ito; Miyazaki; Yamanaka; Mizugaki; Sakamoto
Chemical and Pharmaceutical Bulletin, 1986 , vol. 34, # 4 p. 1634 - 1642
反应条件
1: 72 percent / pyridine / CHCl3 / 2 h / -5 °C
2: 84 percent / ethanol / 8 h / Heating
3: 89 percent / 70percent sodium bis-(2-methoxyethoxy)aluminum hydride in toluene / benzene / 12 h / Ambient temperature
View Scheme
参考文献
Tatee; Kurashige; Shiozawa; Narita; Takei; Ito; Miyazaki; Yamanaka; Mizugaki; Sakamoto
Chemical and Pharmaceutical Bulletin, 1986 , vol. 34, # 4 p. 1634 - 1642
反应条件
1: 63 percent / NaNH2/benzene / 16 h / Heating
2: 88 percent / 70percent sodium bis-(2-methoxyethoxy)aluminum hydride in toluene / benzene / 12 h / Ambient temperature
View Scheme
参考文献
Tatee; Kurashige; Shiozawa; Narita; Takei; Ito; Miyazaki; Yamanaka; Mizugaki; Sakamoto
Chemical and Pharmaceutical Bulletin, 1986 , vol. 34, # 4 p. 1634 - 1642
反应条件
1: 89 percent / NaNH2/benzene / 16 h / Heating
2: 79 percent / 70percent sodium bis-(2-methoxyethoxy)aluminum hydride in toluene / benzene / 12 h / Ambient temperature
View Scheme
参考文献
Tatee; Kurashige; Shiozawa; Narita; Takei; Ito; Miyazaki; Yamanaka; Mizugaki; Sakamoto
Chemical and Pharmaceutical Bulletin, 1986 , vol. 34, # 4 p. 1634 - 1642
反应条件
1: 63 percent / NaNH2/benzene / 16 h / Heating
2: 88 percent / 70percent sodium bis-(2-methoxyethoxy)aluminum hydride in toluene / benzene / 12 h / Ambient temperature
3: 27 percent / 1) NaNH2/benzene / 1) reflux 1.5 h 2) 50 deg C, 12 h
View Scheme
参考文献
Tatee; Kurashige; Shiozawa; Narita; Takei; Ito; Miyazaki; Yamanaka; Mizugaki; Sakamoto
Chemical and Pharmaceutical Bulletin, 1986 , vol. 34, # 4 p. 1634 - 1642
反应条件
in acetic acid
T=70°C; 32 h;
参考文献
Winters, G.; Sala, A.; Paoli, A. De; Conti, M.
Synthesis, 1984 , # 12 p. 1050 - 1052
反应条件
in acetic acid
T=70°C; 24 h;
参考文献
Winters, G.; Sala, A.; Paoli, A. De; Conti, M.
Synthesis, 1984 , # 12 p. 1050 - 1052
参考文献
Nishiwaki,T.
Bulletin of the Chemical Society of Japan, 1976 , vol. 49, p. 3339 - 3340
反应条件
mixture of gaseous nitrogen oxides
anschliessend Behandeln mit wss. Natriumacetat;
参考文献
Musante
Gazzetta Chimica Italiana, 1943 , vol. 73, p. 366,372, 374
