(R)-哌啶-1,3-二羧酸 1-苄酯 3-乙酯合成路线 （共 4 条）
反应条件
sodium hydroxide in tetrahydrofuran; hexane; water
参考文献
Aquila, Brian M.; Bannister, Thomas D.; Cuny, Gregory C.; Hauske, James R.; Heffernan, Michele L.R.; Hoemann, Michael Z.; Kessler, Donald W.; Shao, Liming; Wu, Xinhe; Xie, Roger L.
Patent: US2002/177721 A1, 2002 ;
反应条件
hydrogen; [Rh((S,S,R,R)-Tangphos)NBD][SbF6] in dichloromethane
T=80°C; P=77572.2 Torr; 72 h; Title compound not separated from byproducts;
参考文献
Lei, Aiwen; Chen, Mao; He, Minsheng; Zhang, Xumu
European Journal of Organic Chemistry, 2006 , # 19 p. 4343 - 4347
反应条件
1: 90 percent / H2 / 5 percent Pd-C / aq. ethanol / 36 h / 20 °C / 5171.48 Torr
2: BuLi / -78 °C
3: H2 / [Rh((S,S,R,R)-Tangphos)NBD][SbF6] / CH2Cl2 / 72 h / 80 °C / 77572.2 Torr
View Scheme
参考文献
Lei, Aiwen; Chen, Mao; He, Minsheng; Zhang, Xumu
European Journal of Organic Chemistry, 2006 , # 19 p. 4343 - 4347
反应条件
1: BuLi / -78 °C
2: H2 / [Rh((S,S,R,R)-Tangphos)NBD][SbF6] / CH2Cl2 / 72 h / 80 °C / 77572.2 Torr
View Scheme
参考文献
Lei, Aiwen; Chen, Mao; He, Minsheng; Zhang, Xumu
European Journal of Organic Chemistry, 2006 , # 19 p. 4343 - 4347
