4-(N,N-dimethlyamino)pyridine; triethylamine in dichloromethane T=25°C;

1: succinic acid With dicyclohexyl-carbodiimide; 4-(N,N-dimethlyamino)pyridine in dichloromethane 0.166667 - 0.25 h; Ultrasonication; 2: 2,5,7,8-tetramethyl-2-(4',8',12'-trimethyltridecyl)-6-chromanol in dichloromethane T=25°C;

1: durch Chlormethylierung und Reduktion 2: pyridine View Scheme

1: durch Chlormethylierung und Reduktion 2: pyridine View Scheme

1: alpha-tocopherol hydrogen succinate With 4-methyl-morpholine; isobutyl chloroformate in tetrahydrofuran T=0 - 20°C; 1.75 h; 2: (S)-(-)-2-pyrrolidone-5-carboxylic acid With triethylamine in tetrahydrofuran; DMF (N,N-dimethyl-formamide); water T=0 - 20°C; 3: With hydrogenchloride in dichloromethane; water

1: alpha-tocopherol hydrogen succinate With 4-methyl-morpholine; isobutyl chloroformate in tetrahydrofuran T=0 - 20°C; 1.75 h; 2: bispropylamino polyethylene glycol With triethylamine in tetrahydrofuran; water T=0°C;

4-methyl-morpholine; isobutyl chloroformate in tetrahydrofuran T=0 - 20°C; 2.15 h;