2-(2-氰基苯基)苯甲腈合成路线 （共 37 条）
反应条件
oxygen; lithium chloride; manganese (II) chloride in tetrahydrofuran
T=-5 - 0°C; Inert atmosphere; chemoselective reaction;
参考文献
Cahiez, Gerard; Duplais, Christophe; Buendia, Julien
Angewandte Chemie, International Edition, 2009 , vol. 48, # 36 p. 6731 - 6734
反应条件
manganese; cobalt (II) bromide; triphenylphosphine; trifluoroacetic acid in pyridine; N,N-dimethyl-formamide
T=50°C;
参考文献
Amatore, Muriel; Gosmini, Corinne
Angewandte Chemie - International Edition, 2008 , vol. 47, # 11 p. 2089 - 2092
反应条件
tetrabutylammomium bromide; potassium carbonate; palladium diacetate in N,N-dimethyl-formamide
T=100°C; Heck-type reaction; 28 h;
参考文献
Fournier Dit Chabert, Jeremie; Gozzi, Christel; Lemaire, Marc
Tetrahedron Letters, 2002 , vol. 43, # 10 p. 1829 - 1833
反应条件
trifluoroacetic acid; cobalt(II) dibromide; zinc dibromide in acetonitrile
the mixt. in CH3CN was stirred at room temp., then arylbromide was added, stirred at room temp.; GC analysis;
参考文献
Fillon, Hyacinthe; Gosmini, Corinne; Perichon, Jacques
Journal of the American Chemical Society, 2003 , vol. 125, # 13 p. 3867 - 3870
反应条件
bis(η3-allyl-μ-chloropalladium(II)); dppba in N,N-dimethyl-formamide
T=50°C; 44 h;
参考文献
Shirakawa, Eiji; Murota, Yasubumi; Nakao, Yoshiaki; Hiyama, Tamejiro
Synlett, 1997 , vol. 1997, # 10 p. 1143 - 1144
反应条件
1: With n-butyllithium in tetrahydrofuran; diethyl ether; hexane
T=0°C; Substitution; Dimerization; 0.5 h;
2: With [VO(OEt)Cl2] in tetrahydrofuran; diethyl ether; hexane
T=20°C; Oxidation; Alkylation; 3 h; Further stages.;
参考文献
Hirao, Toshikazu; Takada, Takashi; Ogawa, Akiya
Journal of Organic Chemistry, 2000 , vol. 65, # 5 p. 1511 - 1515
反应条件
1: With n-butyllithium in tetrahydrofuran; diethyl ether; hexane
T=0°C; Substitution; Dimerization; 0.5 h;
2: With [VO(OEt)Cl2] in tetrahydrofuran; diethyl ether; hexane
T=20°C; Oxidation; Alkylation; 3 h; Further stages.;
参考文献
Hirao, Toshikazu; Takada, Takashi; Ogawa, Akiya
Journal of Organic Chemistry, 2000 , vol. 65, # 5 p. 1511 - 1515
反应条件
pyridine; tetra-n-butylammonium tetrafluoroborate in acetonitrile
T=20°C; Electrolysisiron rod as anode; stainless steel grid as cathode;
参考文献
Gomes, Paulo; Fillon, Hyacinthe; Gosmini, Corinne; Labbe, Eric; Perichon, Jacques
Tetrahedron, 2002 , vol. 58, # 42 p. 8417 - 8424
反应条件
pyridine; tetra-n-butylammonium tetrafluoroborate in acetonitrile
T=20°C; Electrolysisiron rod as anode; stainless steel grid as cathode;
参考文献
Gomes, Paulo; Fillon, Hyacinthe; Gosmini, Corinne; Labbe, Eric; Perichon, Jacques
Tetrahedron, 2002 , vol. 58, # 42 p. 8417 - 8424
反应条件
pyridine; tetra-n-butylammonium tetrafluoroborate in acetonitrile
T=20°C; Electrolysisiron rod as anode; stainless steel grid as cathode;
参考文献
Gomes, Paulo; Fillon, Hyacinthe; Gosmini, Corinne; Labbe, Eric; Perichon, Jacques
Tetrahedron, 2002 , vol. 58, # 42 p. 8417 - 8424
