2-甲氧基丙酸合成路线

124-41-4甲醇钠+598-72-12-溴丙酸→4324-37-22-甲氧基丙酸

参考文献

BAYER PHARMACEUTICALS CORPORATION
Patent: WO2006/133006 A2, 2006 ;
Location in patent: Page/Page column 46-47 ;

27871-49-4(S)-(-)-乳酸甲酯+74-88-4甲基碘→4324-37-22-甲氧基丙酸

参考文献

BOEHRINGER INGELHEIM INTERNATIONAL GMBH
Patent: WO2009/109549 A1, 2009 ;
Location in patent: Page/Page column 138-139 ;

67-56-1甲醇+124-41-4甲醇钠+598-72-12-溴丙酸→4324-37-22-甲氧基丙酸

参考文献

BAYER PHARMACEUTICALS CORPORATION
Patent: WO2006/2383 A2, 2006 ;
Location in patent: Page/Page column 49-50 ;

67-56-1甲醇+547-64-8乳酸甲酯→4324-37-22-甲氧基丙酸+75-07-0乙醛+292638-85-8丙烯酸甲酯+79-10-7丙烯酸

参考文献

MYRIANT CORPORATION; OZMERAL, A., Cenan; GLAS, Joseph P.; DASARI, Rajesh; TANIELYAN, Setrak; BHAGAT, Ramesh Deoram; KASIREDDY, Mohan Reddy; SINGH, Ramnik; GNANADESIKAN, Vijay; AUGUSTINE, Robert L.; MORE, Santosh
Patent: WO2013/134385 A1, 2013 ;
Location in patent: Paragraph 0168; 0169 ;

41918-08-5S)-(-)-2-甲氧基丙酸乙酯→4324-37-22-甲氧基丙酸

参考文献

Bales; Horner; Huang; Newcomb; Crich; Greenberg
Journal of the American Chemical Society, 2001 , vol. 123, # 16 p. 3623 - 3629

535-11-52-溴丙酸乙酯→4324-37-22-甲氧基丙酸

参考文献

PPG Industries, Inc.
Patent: US4314842 A1, 1982 ;

598-72-12-溴丙酸→4324-37-22-甲氧基丙酸

参考文献

Sigma-Tau Industrie Farmaceutiche Riunite S.P.A.
Patent: US4551477 A1, 1985 ;

17639-76-82-甲氧基丙酸甲酯→4324-37-22-甲氧基丙酸

参考文献

Rodewald; Plazek
Roczniki Chemii, 1935 , vol. 15, p. 83
Chem. Zentralbl., 1935 , vol. 106, # II p. 2045

4324-39-4O-甲基-L-乳酸乙酯→4324-37-22-甲氧基丙酸

参考文献

Yonezawa, Noriyuki; Hino, Tetsuo; Tokita, Yoshimi; Matsuda, Kazuhisa; Ikeda, Tomiki
Tetrahedron, 1997 , vol. 53, # 42 p. 14287 - 14296

25774-52-1→4324-37-22-甲氧基丙酸

参考文献

Ruechardt,C. et al.
Chemische Berichte, 1969 , vol. 102, p. 3922 - 3946