5-苯基硫代-1,2-二氨基苯合成路线 （共 8 条）
反应条件
hydrogen; nickel in ethanol P=2660 Torr; 12 h;
参考文献
Cortes, Eduardo Cortes; Mendoza, Rafael Sosa; Gutierrez, Maximiliano Santibanez; De Cortes, Olivia Garcia-Mellado
Journal of Heterocyclic Chemistry, 2004 , vol. 41, # 2 p. 273 - 276
反应条件
stannous chloride; sodium; potassium hydrogencarbonate in hydrogenchloride; chloroform
参考文献
Syntex (U.S.A.) Inc.
Patent: US3965113 A1, 1976 ;
反应条件
1: K2CO3 / dimethylformamide / 6 h / Heating 2: H2 / Pd/C / ethanol / 20 °C / 3102.89 Torr View Scheme
参考文献
Rastogi; Sharma
Archiv der Pharmazie, 1983 , vol. 316, # 7 p. 638 - 638
反应条件
1: K2CO3 / dimethylformamide / 6 h / Heating 2: H2 / Pd/C / ethanol / 20 °C / 3102.89 Torr View Scheme
参考文献
Rastogi; Sharma
Archiv der Pharmazie, 1983 , vol. 316, # 7 p. 638 - 638
反应条件
sodium hydroxide in N-methyl-acetamide; water; potassium carbonate; acetic acid
参考文献
Hoechst Aktiengesellschaft
Patent: US3954791 A1, 1976 ;
反应条件
1: 2-methyl-2-thiopseudourea sulfate; methyl chloroformate With sodium hydroxide in water T=3 - 6°C; 0.666667 h; 2: 1,2-diamino-4-phenylthiobenzene With acetic acid in ethanol; water T=95°C; 24 h;
参考文献
Cortes, Eduardo Cortes; Mendoza, Rafael Sosa; Gutierrez, Maximiliano Santibanez; De Cortes, Olivia Garcia-Mellado
Journal of Heterocyclic Chemistry, 2004 , vol. 41, # 2 p. 273 - 276
反应条件
in ethanol
8 h; Heating;
参考文献
Singh; Naim; Sharma; Gupta; Katiyar
Indian Journal of Chemistry - Section B Organic Chemistry Including Medicinal Chemistry, 1989 , vol. 28, # 5 p. 397 - 402
反应条件
1: 60 percent / ethanol / 8 h / Heating
2: 82 percent / pyridine / 1 h / Heating
3: 82.6 percent / KMnO4 / acetic acid / 2 h / Ambient temperature
4: 73.5 percent / aq. NaOH / ethanol / 2 h / Ambient temperature
View Scheme
参考文献
Singh; Naim; Sharma; Gupta; Katiyar
Indian Journal of Chemistry - Section B Organic Chemistry Including Medicinal Chemistry, 1989 , vol. 28, # 5 p. 397 - 402
