1-([1,1'-联苯]-4-基氧基)-3,3-二甲基-1-(1H-1,2,4-三唑-1-基)丁烷-2-酮合成路线 （共 6 条）
反应条件
in water; isopropyl alcohol
参考文献
Bayer Aktiengesellschaft
Patent: US4510314 A1, 1985 ;
反应条件
sodium tetrahydroborate in tetrahydrofuran 1 h; Ambient temperature;
参考文献
Reuther, Wolfgang; Ruland, Alfred; Baus, Ulf
Liebigs Annalen der Chemie, 1988 , p. 235 - 240
反应条件
palladium on activated charcoal; potassium carbonate; 2-dicyclohexylphosphino-1,1'-biphenyl in N,N-dimethyl acetamide; water
T=105°C; Suzuki Coupling; 2 h; Schlenk techniqueInert atmosphereMicrowave irradiation; Temperature;
参考文献
Herrera Cano, Natividad; Santiago, Ana N.
Tetrahedron, 2014 , vol. 70, # 2 p. 280 - 285
反应条件
bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; triphenylphosphine; cesium fluoride in toluene
T=100°C; Stille Cross Coupling; 48 h; Schlenk techniqueInert atmosphere; SolventReagent/catalystConcentrationTemperature; Overall yield = 77 percent;
参考文献
Herrera Cano, Natividad; Santiago, Ana N.
Tetrahedron, 2014 , vol. 70, # 2 p. 280 - 285
反应条件
bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; triphenylphosphine; cesium fluoride in toluene
T=100°C; Stille Cross Coupling; 48 h; Schlenk techniqueInert atmosphere; Reagent/catalyst;
参考文献
Herrera Cano, Natividad; Santiago, Ana N.
Tetrahedron, 2014 , vol. 70, # 2 p. 280 - 285
反应条件
1.1: sodium; ammonia
1.2: 1.5 h / |UV-irradiation
2.1: bis-triphenylphosphine-palladium(II) chloride; triphenylphosphine; cesium fluoride; copper(l) iodide / toluene / 48 h / 100 °C / |Schlenk technique; |Inert atmosphere
View Scheme
参考文献
Herrera Cano, Natividad; Santiago, Ana N.
Tetrahedron, 2014 , vol. 70, # 2 p. 280 - 285
