3-氨基-1,1,1-三氟丙烷-2-醇合成路线 （共 4 条）
反应条件
ammonia in water T=20°C; 22 h;
参考文献
ASTRAZENECA AB; SCHERING AG
Patent: WO2007/46747 A1, 2007 ;
Location in patent: Page/Page column 29 ;
WO 2007/046747 A1
反应条件
ethanol; nickel Hydrogenation;
参考文献
Shao, Yi-Ming; Yang, Wen-Bin; Kuo, Tun-Hsun; Tsai, Keng-Chang; Lin, Chun-Hung; Yang, An-Suei; Liang, Po-Huang; Wong, Chi-Huey
Bioorganic and Medicinal Chemistry, 2008 , vol. 16, # 8 p. 4652 - 4660
反应条件
KOCl; water T=0°C; zuletzt unter Erwaermen;
参考文献
Jones
Journal of the American Chemical Society, 1948 , vol. 70, p. 143
反应条件
silica gel in cyclohexane; benzene Resolution of racemate;
参考文献
Sorochinsky, Alexander E.; Katagiri, Toshimasa; Ono, Taizo; Wzorek, Alicja; Acena, Jose Luis; Soloshonok, Vadim A.
Chirality, 2013 , vol. 25, # 6 p. 365 - 368
