2-(1-苄基-1H-吲哚-3-基)-乙胺合成路线 （共 15 条）
反应条件
hydrogen; rhodium on alumina in tetrahydrofuran P=2068.6 Torr; 48 h;
参考文献
Jahangir; Brook; Maclean; Holland
Tetrahedron, 1987 , vol. 43, # 24 p. 5761 - 5768
反应条件
hydrazine hydrate in ethanol Heating;
参考文献
Liu, Yanqin; Luo, Shengjun; Fu, Xingnian; Fang, Fang; Zhuang, Zeyang; Xiong, Wanting; Jia, Xueshun; Zhai, Hongbin
Organic Letters, 2006 , vol. 8, # 1 p. 115 - 118
反应条件
1: tryptamine With sodium hydride in N,N-dimethyl-formamide T=20°C; 0.5 h; 2: benzyl chloride in N,N-dimethyl-formamide T=50°C; 2 h;
参考文献
Novak; Hanania; Kovacs; Kolonits; Szantay
Synthesis, 2001 , # 1 p. 108 - 118
反应条件
lithium aluminium tetrahydride in tetrahydrofuran 1.5 h; Heating;
参考文献
Guengoer, Timur; Malabre, Patrice; Teulon, Jean-Marie; Camborde, Francoise; Meignen, Joelle; et al.
Journal of Medicinal Chemistry, 1994 , vol. 37, # 25 p. 4307 - 4316
反应条件
trifluoroacetic acid in dichloromethane T=20°C; Hydrolysis; 1 h;
参考文献
Benson, Scott C.; Lee, Lily; Yang, Lydie; Snyder, John K.
Tetrahedron, 2000 , vol. 56, # 9 p. 1165 - 1180
反应条件
1: 71 percent / AcONH4 / 0.5 h / Heating 2: 58 percent / LiAlH4 / tetrahydrofuran / 1.5 h / Heating View Scheme
参考文献
Merour, J. Y.; Buzas, A.
Synthetic Communications, 1988 , vol. 18, # 18 p. 2331 - 2336
反应条件
1: 78 percent / NaH / benzene / 1.) reflux, 20 min; 2.) 12 h, room temp. 2: 95 percent / H2, / 5percent Rh-Al2O3 / tetrahydrofuran; various solvent(s) / 48 h / 2068.6 Torr View Scheme
参考文献
Jahangir; Brook; Maclean; Holland
Tetrahedron, 1987 , vol. 43, # 24 p. 5761 - 5768
反应条件
1: 78 percent / NaH / benzene / 1.) reflux, 20 min; 2.) 12 h, room temp. 2: 95 percent / H2, / 5percent Rh-Al2O3 / tetrahydrofuran; various solvent(s) / 48 h / 2068.6 Torr View Scheme
参考文献
Guengoer, Timur; Malabre, Patrice; Teulon, Jean-Marie; Camborde, Francoise; Meignen, Joelle; et al.
Journal of Medicinal Chemistry, 1994 , vol. 37, # 25 p. 4307 - 4316
反应条件
2-(tert-butoxycarbonyloxyimino)-2-phenylacetonitrile; potassium hydride; trifluoroacetic acid Multistep reaction;
参考文献
Teichert, Johannes F.; Fananas-Mastral, Martin; Feringa, Ben L.
Synthesis, 2012 , vol. 44, # 3 art. no. T104711SS, p. 409 - 416
反应条件
1: 93 percent / toluene / 10 h / Heating 2: 98.5 percent / NaH / dimethylformamide; various solvent(s) / 20 - 55 °C 3: 95 percent / hydrazine hydrate / ethanol / Heating View Scheme
参考文献
Benson, Scott C.; Lee, Lily; Yang, Lydie; Snyder, John K.
Tetrahedron, 2000 , vol. 56, # 9 p. 1165 - 1180
