2,3-二氢-1H-喹啉-4-酮合成路线 （共 51 条）
反应条件
palladium 10 on activated carbon; sodium hydroxide in water; isopropyl alcohol 16 h; Inert atmosphereReflux;
参考文献
Lange, Jens; Bissember, Alex C.; Banwell, Martin G.; Cade, Ian A.
Australian Journal of Chemistry, 2011 , vol. 64, # 4 p. 454 - 470
反应条件
1: 30 percent / pyridine / 2 h / Heating 2: 89 percent / NaBH4 / methanol / 0.17 h 3: 56 percent / p-TsOH / toluene / 0.5 h / Heating View Scheme
参考文献
Toekes, Adrienne L.; Antus, Sandor
Liebigs Annalen der Chemie, 1994 , # 9 p. 911 - 916
反应条件
bromine; cesium fluoride in acetonitrile T=20°C;
参考文献
Fang, Yuesi; Rogness, Donald C.; Larock, Richard C.; Shi, Feng
Journal of Organic Chemistry, 2012 , vol. 77, # 14 p. 6262 - 6270
反应条件
sodium azide; sulfuric acid 24 h; Ambient temperature; Title compound not separated from byproducts;
参考文献
Grunewald, Gary L.; Dahanukar, Vilas H.; Ching, Piao; Criscione, Kevin R.
Journal of Medicinal Chemistry, 1996 , vol. 39, # 18 p. 3539 - 3546
反应条件
nitrobenzene T=170 - 180°C;
参考文献
Johnson; Buell
Journal of the American Chemical Society, 1952 , vol. 74, p. 4513,4515
Journal of the American Chemical Society, 1952 , vol. 74, p. 4517,4519
反应条件
ammonium chloride; phenethylamine; benzene
参考文献
Johnson; Buell
Journal of the American Chemical Society, 1952 , vol. 74, p. 4513,4515
Journal of the American Chemical Society, 1952 , vol. 74, p. 4517,4519
反应条件
T=180°C; unter Stickstoff;
参考文献
Johnson; Buell
Journal of the American Chemical Society, 1952 , vol. 74, p. 4513,4515
Journal of the American Chemical Society, 1952 , vol. 74, p. 4517,4519
参考文献
Johnson; Buell
Journal of the American Chemical Society, 1952 , vol. 74, p. 4513,4515
Journal of the American Chemical Society, 1952 , vol. 74, p. 4517,4519
反应条件
1.1: sodium hydride / N,N-dimethyl-formamide; mineral oil / 2 h / 20 °C / Inert atmosphere 1.2: 12 h / 80 °C 2.1: cesium fluoride / acetonitrile / 24 h / 20 °C View Scheme
参考文献
Fang, Yuesi; Rogness, Donald C.; Larock, Richard C.; Shi, Feng
Journal of Organic Chemistry, 2012 , vol. 77, # 14 p. 6262 - 6270
反应条件
1: DMAP / tetrahydrofuran 2: tetrahydrofuran / 0 °C 3: H2, TFA / Pd/C / ethyl acetate; ethanol 4: TFA View Scheme
参考文献
Higuchi, Robert I.; Edwards, James P.; Caferro, Thomas R.; Ringgenberg, Josef D.; Kong, James W.; Hamann, Lawrence G.; Arienti, Kristen L.; Marschke, Keith B.; Davis, Robert L.; Farmer, Luc J.; Jones, Todd K.
Bioorganic and Medicinal Chemistry Letters, 1999 , vol. 9, # 9 p. 1335 - 1340
