2-(3-氯-2-羟基丙氧基)-苯甲腈合成路线 （共 4 条）
反应条件
sodium hydroxide; tetrabutylammomium bromide; potassium carbonate
T=106°C; 0.283333 h;
参考文献
Pchelka, Beata K.; Loupy, Andre; Petit, Alain
Tetrahedron, 2006 , vol. 62, # 47 p. 10968 - 10979
参考文献
Kreighbaum; Matier; Dennis; Minielli; Deitchman; Perhach Jr.; Comer
Journal of Medicinal Chemistry, 1980 , vol. 23, # 3 p. 285 - 289
反应条件
1: 1N aq. NaOH / tetrahydrofuran / 0.67 h / 20 - 60 °C
2: 0.5 h / 120 - 140 °C
View Scheme
参考文献
Kreighbaum; Matier; Dennis; Minielli; Deitchman; Perhach Jr.; Comer
Journal of Medicinal Chemistry, 1980 , vol. 23, # 3 p. 285 - 289
反应条件
sodium hydroxide in tetrahydrofuran
T=20 - 60°C; 0.666667 h;
参考文献
Kreighbaum; Matier; Dennis; Minielli; Deitchman; Perhach Jr.; Comer
Journal of Medicinal Chemistry, 1980 , vol. 23, # 3 p. 285 - 289
