2-(4-硝基苯基)吡啶合成路线 （共 46 条）
反应条件
tetrakis(triphenylphosphine) palladium(0); potassium carbonate in ethanol T=100°C; Suzuki Coupling; 18 h; Inert atmosphere;
参考文献
Goggins, Sean; Rosevere, Eleanor; Bellini, Clement; Allen, Joseph C.; Marsh, Barrie J.; Mahon, Mary F.; Frost, Christopher G.
Organic and Biomolecular Chemistry, 2014 , vol. 12, # 1 p. 47 - 52
反应条件
palladium diacetate; potassium carbonate; triphenylphosphine; copper(l) iodide in tetrahydrofuran Suzuki-Miyaura cross-coupling reaction; Heating;
参考文献
Hodgson, Paul B.; Salingue, Fabrice H.
Tetrahedron Letters, 2004 , vol. 45, # 4 p. 685 - 687
反应条件
tetrakis(triphenylphosphine) palladium(0); tetrabutyl ammonium fluoride; silver(l) oxide in tetrahydrofuran; N,N-dimethyl-formamide T=90°C; 18 h;
参考文献
Napier, Spencer; Marcuccio, Sebastian M.; Tye, Heather; Whittaker, Mark
Tetrahedron Letters, 2008 , vol. 49, # 44 p. 6314 - 6315
反应条件
tris-(dibenzylideneacetone)dipalladium(0); 2-(dicyclohexylphosphino)-2',4',6'-tri-i-propyl-1,1’-biphenyl in tetrahydrofuran T=65°C; Negishi cross-coupling; 1 h; Inert atmosphere;
参考文献
Luzung, Michael R.; Patel, Jigar S.; Yin, Jingjun
Journal of Organic Chemistry, 2010 , vol. 75, # 23 p. 8330 - 8332
反应条件
T=180°C; P=0.5 Torr; 4 h;
参考文献
Katritzky, Alan R.; Chermprapai, Amornsri; Patel, Ranjan C.; Tarraga-Tomas, Alberto
Journal of Organic Chemistry, 1982 , vol. 47, # 3 p. 492 - 497
反应条件
T=160°C; P=0.5 Torr; 4 h;
参考文献
Katritzky, Alan R.; Chermprapai, Amornsri; Patel, Ranjan C.; Tarraga-Tomas, Alberto
Journal of Organic Chemistry, 1982 , vol. 47, # 3 p. 492 - 497
反应条件
nitronium tetrafluoroborate; oxygen; copper diacetate in 1,2,3-trichloro propane T=130°C; 24 h;
参考文献
Zhang, Lin; Liu, Zhenhua; Li, Huiqin; Fang, Guichun; Barry, Badru-Deen; Belay, Tuemay Abadi; Bi, Xihe; Liu, Qun
Organic Letters, 2011 , vol. 13, # 24 p. 6536 - 6539
反应条件
bis-triphenylphosphine-palladium(II) chloride; lithium chloride in tetrahydrofuran; N,N-dimethyl-formamide T=80°C; 22 h;
参考文献
Curran, Dennis P.; Hoshino, Masahide
Journal of Organic Chemistry, 1996 , vol. 61, # 19 p. 6480 - 6481
反应条件
1.1: n-BuLi / tetrahydrofuran; hexane / 16 h / 20 °C 1.2: 75 percent / isopropanol / tetrahydrofuran; hexane / 4 h / Heating 2.1: 82 percent / PPh3; K2CO3; Pd(OAc)2 / CuI / tetrahydrofuran / Heating View Scheme
参考文献
Sakashita, Shohei; Takizawa, Miho; Sugai, Juugaku; Ito, Hajime; Yamamoto, Yasunori
Organic Letters, 2013 , vol. 15, # 17 p. 4308 - 4311
反应条件
palladium diacetate; potassium carbonate; triphenylphosphine in toluene 12 h; RefluxInert atmosphere;
参考文献
Xu, Jimin; Cheng, Guolin; Su, Deyong; Liu, Yantao; Wang, Xinyan; Hu, Yuefei
Chemistry - A European Journal, 2009 , vol. 15, # 47 p. 13105 - 13110
