3,4-二甲基色烯-2-酮合成路线 （共 9 条）
反应条件
hydrogenchloride in ethanol
7 h; Heating;
参考文献
Motoyoshiya, Jiro; Teranishi, Akinori; Mikoshiba, Reiko; Yamamoto, Iwao; Gotoh, Haruo
Journal of Organic Chemistry, 1980 , vol. 45, # 26 p. 5385 - 5387
反应条件
N,N-diethylaniline
48 h; Inert atmosphereRefluxNeat (no solvent);
参考文献
Martin, Tioga J.; Vakhshori, Venus G.; Tran, Yang S.; Kwon, Ohyun
Organic Letters, 2011 , vol. 13, # 10 p. 2586 - 2589
反应条件
1: 92 percent / CH2Cl2 / 20 °C
2: 41 percent / Na2Te / tetrahydrofuran / -20 - 20 °C
View Scheme
参考文献
Dittmer, Donald C.; Li, Qun; Avilov, Dimitry V.
Journal of Organic Chemistry, 2005 , vol. 70, # 12 p. 4682 - 4686
反应条件
1: triphenylphosphine / benzene / 17 h / Reflux; Inert atmosphere
2: N,N-diethylaniline / 48 h / Inert atmosphere; Reflux; Neat (no solvent)
View Scheme
参考文献
Martin, Tioga J.; Vakhshori, Venus G.; Tran, Yang S.; Kwon, Ohyun
Organic Letters, 2011 , vol. 13, # 10 p. 2586 - 2589
反应条件
propionic acid sodium salt
T=200°C;
参考文献
Heilbron et al.
Journal of the Chemical Society, 1933 , p. 430,432
Journal of the Chemical Society, 1934 , p. 1581
反应条件
sulfuric acid
T=75°C;
参考文献
Peters; Simonis
Chemische Berichte, 1908 , vol. 41, p. 831
反应条件
in chloroform
36 h; Heating;
参考文献
Patil, Vinayak O.; Kelkar, Shriniwas L.; Wadia, Murzban S.
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1987 , vol. 26, p. 674 - 675
反应条件
sodium hydride; dicyclohexyl-carbodiimide
1.) benzene, room temp., 8 h; 2.) benzene, THF, room temp., 6 h; Yield given. Multistep reaction;
参考文献
Falsone, Gioacchino; Spur, Bernd; Wingen, Peter H.
Archiv der Pharmazie (Weinheim, Germany), 1983 , vol. 316, # 9 p. 763 - 766
参考文献
Peters; Simonis
Chemische Berichte, 1908 , vol. 41, p. 831
