(R)-1,2-丙二醇合成路线

75-56-9环氧丙烷→4254-14-2(R)-1,2-丙二醇+16088-62-3S-环氧丙烷

参考文献

Schaus, Scott E.; Brandes, Bridget D.; Larrow, Jay F.; Tokunaga, Makoto; Hansen, Karl B.; Gould, Alexandra E.; Furrow, Michael E.; Jacobsen, Eric N.
Journal of the American Chemical Society, 2002 , vol. 124, # 7 p. 1307 - 1315

20263-26-7→4254-14-2(R)-1,2-丙二醇

参考文献

Xing, Dongxia; Chen, Ping; Keil, Robert; Kilts, Clinton D.; Shi, Bing; Camp, Vernon M.; Malveaux, Gene; Ely, Timothy; Owens, Michael J.; Votaw, John; Davis, Margaret; Hoffman, John M.; BaKay, Roy A. E.; Subramanian, Thygarajan; Watts, Ray L.; Goodman, Mark M.
Journal of Medicinal Chemistry, 2000 , vol. 43, # 4 p. 639 - 648

17392-83-5D-(+)-乳酸甲酯→4254-14-2(R)-1,2-丙二醇

参考文献

Kuriyama, Wataru; Matsumoto, Takaji; Ogata, Osamu; Ino, Yasunori; Aoki, Kunimori; Tanaka, Shigeru; Ishida, Kenya; Kobayashi, Tohru; Sayo, Noboru; Saito, Takao
Organic Process Research and Development, 2012 , vol. 16, # 1 p. 166 - 171

116-09-6羟基丙酮→4254-15-3(S)-(+)-1,2-丙二醇+4254-14-2(R)-1,2-丙二醇

参考文献

Thanos, Iordanes; Simon, Helmut
Angewandte Chemie, 1986 , vol. 98, # 5 p. 455 - 456

60456-23-7(S)-缩水甘油→4254-14-2(R)-1,2-丙二醇

参考文献

GILEAD SCIENCES, INC.
Patent: EP1243590 A2, 2002 ;
Location in patent: Page 8 ;

61597-96-4→4254-14-2(R)-1,2-丙二醇

参考文献

IHARA CHEMICAL INDUSTRY CO., LTD.
Patent: EP1146032 A1, 2001 ;

1369852-93-6→4254-14-2(R)-1,2-丙二醇

参考文献

Petursson, Sigthor; Jonsdottir, Sigridur
Tetrahedron Asymmetry, 2012 , vol. 23, # 2 p. 157 - 163

176097-26-0→4254-14-2(R)-1,2-丙二醇

参考文献

Vanhessche, Koen P. M.; Sharpless, K. Barry
Chemistry - A European Journal, 1997 , vol. 3, # 4 p. 517 - 522

17392-83-5D-(+)-乳酸甲酯→4254-15-3(S)-(+)-1,2-丙二醇+4254-14-2(R)-1,2-丙二醇

参考文献

Takasago International Corporation
Patent: EP2141142 A1, 2010 ;
Location in patent: Page/Page column 17 ;

87037-69-2→4254-14-2(R)-1,2-丙二醇

参考文献

McGrath, John W.; Hammerschmidt, Friedrich; Preusser, Werner; Quinn, John P.; Schweifer, Anna
Organic and Biomolecular Chemistry, 2009 , vol. 7, # 9 p. 1944 - 1953