(3,3-二甲基-1-丁炔)-苯合成路线 （共 61 条）
反应条件
(i) nBuLi, THF, hexane, (ii) /BRN= 1961313/, (iii) I2, Et2O; Multistep reaction;
参考文献
Suzuki,A. et al.
Journal of the American Chemical Society, 1973 , vol. 95, p. 3080 - 3081
反应条件
in dimethyl sulfoxide
T=35 - 40°C; 7 h; Irradiation;
参考文献
Russell, Glen A.; Ngoviwatchai, Preecha
Tetrahedron Letters, 1986 , vol. 27, # 30 p. 3479 - 3482
反应条件
in dimethyl sulfoxide
T=35 - 40°C; 24 h; Irradiation;
参考文献
Russell, Glen A.; Ngoviwatchai, Preecha
Tetrahedron Letters, 1986 , vol. 27, # 30 p. 3479 - 3482
反应条件
in benzene
T=35 - 40°C; 30 h; Irradiation;
参考文献
Russell, Glen A.; Ngoviwatchai, Preecha
Tetrahedron Letters, 1986 , vol. 27, # 30 p. 3479 - 3482
反应条件
zinc(II) chloride; Pd(PPh3)2 in tetrahydrofuran
T=22°C; 0.1 h; Variation of catalyst.; Product distributionMechanism;
参考文献
Negishi, Ei-ichi; Takahashi, Tamotsu; Akiyoshi, Kazunari
Journal of Organometallic Chemistry, 1987 , vol. 334, p. 181 - 194
反应条件
methyl-magnesium iodide; magnesium iodide in diethyl ether
参考文献
Coulomb-Delbecq,F. et al.
Bulletin de la Societe Chimique de France, 1976 , p. 533 - 540
反应条件
in dichloromethane
15 h; Heating;
参考文献
Marcuzzi, Franco; Modena, Giorgio
Journal of Organic Chemistry, 1982 , vol. 47, # 23 p. 4577 - 4579
反应条件
1: Br2 / diethyl ether / 2 h / -10 °C
2: 70 percent / KOH / H2O; diethyl ether / 180 - 220 °C
3: 1.) MeI, Li / 1.) Et2O, 20 deg C, 1 h; 2.) 20 deg C, 12 h
4: 85 percent / CaCl2, CuCl, Cu, 12N HCl / diethyl ether; petroleum ether / 1 h / 5 °C
5: 1.) Mg / 1.) Et2O; 2.) 12 h, RT; 2 h, reflux
View Scheme
参考文献
Mesnard, Danielle; Bernadou, Francoise; Miginiac, Leone
Journal of Chemical Research, Miniprint, 1981 , # 9 p. 3216 - 3245
反应条件
1: 70 percent / KOH / H2O; diethyl ether / 180 - 220 °C
2: 1.) MeI, Li / 1.) Et2O, 20 deg C, 1 h; 2.) 20 deg C, 12 h
3: 85 percent / CaCl2, CuCl, Cu, 12N HCl / diethyl ether; petroleum ether / 1 h / 5 °C
4: 1.) Mg / 1.) Et2O; 2.) 12 h, RT; 2 h, reflux
View Scheme
参考文献
Mesnard, Danielle; Bernadou, Francoise; Miginiac, Leone
Journal of Chemical Research, Miniprint, 1981 , # 9 p. 3216 - 3245
反应条件
1: aq. K2SO4
2: (pyrolysis)
View Scheme
参考文献
Truce,W.E.; Wolf,G.C.
Journal of Organic Chemistry, 1971 , vol. 36, # 13 p. 1727 - 1732
