hydrogen; nickel in tetrahydrofuran; water T=25 - 30°C; P=3750.38 Torr; 1 h; Product distribution / selectivity;

1: KOH / ethanol / 2.78 h / -5 - 6 °C 2: 1) H2, 2) NaBH4, aq. NaOH / 1) Pd/C / 1) THF, 40-45 psi, 2) RT, 3 h View Scheme

1: 89.0 percent Chromat. / H2SO4 / acetic acid / 1.5 h / 104 °C / other acid catalysts 2: KOH / ethanol / 2.78 h / -5 - 6 °C 3: 1) H2, 2) NaBH4, aq. NaOH / 1) Pd/C / 1) THF, 40-45 psi, 2) RT, 3 h View Scheme