2-(吡咯烷-1-基)乙烷硫醇合成路线 （共 3 条）
反应条件
1: 2-amino-5-bromothiazole monohydrobromide With sodium hydrogencarbonate in isopropyl alcohol Industry scale; 2: 2-(pyrrolidin-1-yl)ethanethiol in isopropyl alcohol T=60 - 70°C; 97.25 h; Industry scale;
参考文献
Bueno Melendo, Ana Belen; Agejas-Chicharro, Francisco Javier
Patent: US2010/160395 A1, 2010 ;
Location in patent: Page/Page column 3 ;
反应条件
in toluene
T=20 - 50°C; 19 h;
参考文献
BAYER SCHERING PHARMA AKTIENGESELLSCHAFT
Patent: US2011/312930 A1, 2011 ;
Location in patent: Page/Page column 55 ;
US 20110312930 A1
参考文献
Kolloff et al.
Journal of the American Chemical Society, 1949 , vol. 71, p. 3988
