2-氨基-5-氰基吡啶合成路线

参考文献

Caldwell et al.
Journal of the American Chemical Society, 1944 , vol. 66, p. 1479,1482
Full Text Show Details
Vejdelek
Chemicke Listy, 1952 , vol. 46, p. 770
Chem.Abstr., 1953 , p. 11191

4214-73-72-氨基-5-氰基吡啶

468068-28-26-氨基吡啶-3-碳胺肟+

329-89-56-氨基烟酰胺

参考文献

US2007/232583 A1, ;

Page/Page column 43 ;
US 20070232583 A1

4214-73-72-氨基-5-氰基吡啶

468068-28-26-氨基吡啶-3-碳胺肟

参考文献

Journal of Medicinal Chemistry, , vol. 50, # 15 p. 3442 - 3456

4214-73-72-氨基-5-氰基吡啶

477871-32-22-氨基-3-溴-5-氰基吡啶

参考文献

WO2005/90337 A1, ;

Page/Page column 42-43 ;
WO 2005/090337 A1

4214-73-72-氨基-5-氰基吡啶

94805-52-43-氰基-6-羟基吡啶

参考文献

Yasuda; Sakamoto; Sashida; Ueda; Morimoto; Nagasawa
Bioscience, Biotechnology and Biochemistry, 1995 , vol. 59, # 4 p. 572 - 575

4214-73-72-氨基-5-氰基吡啶

156973-09-06-氨基-(9ci)-3-吡啶甲胺

参考文献

PFIZER INC.
Patent: WO2005/63739 A1, 2005 ;
Location in patent: Page/Page column 121 ;
WO 2005/063739 A1

4214-73-72-氨基-5-氰基吡啶

69879-22-72-氨基-5-醛基吡啶

参考文献

Kureha Corporation
Patent: EP1724263 A1, 2006 ;
Location in patent: Page/Page column 55 ;

107-20-0一氯乙醛+

4214-73-72-氨基-5-氰基吡啶

106850-34-4咪唑[1,2-A]吡啶-6-甲腈

参考文献

Laboratorios Almirall, S.A.
Patent: EP2202232 A1, 2010 ;
Location in patent: Page/Page column 55 ;

4214-73-72-氨基-5-氰基吡啶

106850-34-4咪唑[1,2-A]吡啶-6-甲腈

参考文献

SU, Wei-Guo; JIA, Hong; DAI, Guangxiu
Patent: US2012/245178 A1, 2012 ;
US 20120245178 A1

4214-73-72-氨基-5-氰基吡啶+

70-23-53-溴丙酮酸乙酯

214958-33-56-氰基咪唑并[1,2-a]吡啶-2-羧酸乙酯

参考文献

Sundberg, Richard J.; Biswas, Sujay; Murthi, Krishna Kumar; Rowe, Donna; McCall, John W.; Dzimianski, Michael T.
Journal of Medicinal Chemistry, 1998 , vol. 41, # 22 p. 4317 - 4328