2-氯-1-(2-甲基苯基)乙酮合成路线 （共 13 条）
反应条件
water T=125°C; 0.416667 h; microwave irradiation;
参考文献
Utsukihara, Takamitsu; Nakamura, Hiroaki; Watanabe, Masashige; Akira Horiuchi
Tetrahedron Letters, 2006 , vol. 47, # 52 p. 9359 - 9364
反应条件
Oxonereg;; ammonium chloride in methanol
T=20°C; 24 h;
参考文献
Zhou, Zhong Shi; Li, Li; He, Xue Han
Chinese Chemical Letters, 2012 , vol. 23, # 11 p. 1213 - 1216,4
反应条件
chloro-trimethyl-silane; potassium nitrate in dichloromethane
T=60°C; 18 h;
参考文献
Prakash, G.K. Sxurya; Ismail, Rehana; Garcia, Jessica; Panja, Chiradeep; Rasul, Golam; Mathew, Thomas; Olah, George A.
Tetrahedron Letters, 2011 , vol. 52, # 11 p. 1217 - 1221
反应条件
pyridine; formic acid; chlorosulphonyl isocyanate in acetonitrile
T=0 - 10°C; Inert atmosphere;
参考文献
Wang, You-Qing; Yu, Chang-Bin; Wang, Da-Wei; Wang, Xiao-Bing; Zhou, Yong-Gui
Organic Letters, 2008 , vol. 10, # 10 p. 2071 - 2074
反应条件
hydrogenchloride in diethyl ether
T=-20°C; 3 h;
参考文献
Hagishita, Sanji; Seno, Kaoru; Kamata, Susumu; Haga, Nobuhiro; Ishihara, Yasunobu; Ishikawa, Michio; Shimamura, Mayumi
Bioorganic and Medicinal Chemistry, 1997 , vol. 5, # 7 p. 1433 - 1446
反应条件
chlorine dioxide in tetrachloromethane
T=52 - 54°C; 2 h; Further byproducts given. Title compound not separated from byproducts;
参考文献
Kwiecien, Halina; Jalowiczor, Jozef
Polish Journal of Chemistry, 1986 , vol. 60, # 7-12 p. 811 - 824
反应条件
chlorine dioxide in tetrachloromethane
T=52 - 54°C; 2 h; Further byproducts given;
参考文献
Kwiecien, Halina; Jalowiczor, Jozef
Polish Journal of Chemistry, 1986 , vol. 60, # 7-12 p. 811 - 824
反应条件
chlorine dioxide in tetrachloromethane
T=52 - 54°C; 2 h; Further byproducts given;
参考文献
Kwiecien, Halina; Jalowiczor, Jozef
Polish Journal of Chemistry, 1986 , vol. 60, # 7-12 p. 811 - 824
反应条件
water; sodium chloride
T=80°C; 2 h; microwave irradiation;
参考文献
Utsukihara, Takamitsu; Nakamura, Hiroaki; Watanabe, Masashige; Akira Horiuchi
Tetrahedron Letters, 2006 , vol. 47, # 52 p. 9359 - 9364
反应条件
1: SOCl2 / 2 h / Ambient temperature
2: diethyl ether / 0.5 h / 0 °C
3: concd aq. HCl / diethyl ether / 3 h / -20 °C
View Scheme
参考文献
Hagishita, Sanji; Seno, Kaoru; Kamata, Susumu; Haga, Nobuhiro; Ishihara, Yasunobu; Ishikawa, Michio; Shimamura, Mayumi
Bioorganic and Medicinal Chemistry, 1997 , vol. 5, # 7 p. 1433 - 1446
