4-氧代哌啶酮盐酸盐合成路线

41979-39-94-氧代哌啶酮盐酸盐+18880-04-13,4-二氯苄溴→220772-52-11-(3,4-二氯苄基)-4-哌啶酮

参考文献

Syntex (U.S.A.) LLC
Patent: US6339087 B1, 2002 ;
Location in patent: Page column 63 ;
US 6339087 B1

41979-39-94-氧代哌啶酮盐酸盐+1073-70-7对氯苯肼盐酸盐→19685-84-88-氯-2,3,4,5-四氢-1H-吡啶并[4,3-b]吲哚

参考文献

Yin, Zhou; Whittell, Louise R.; Wang, Yao; Jergic, Slobodan; Liu, Michael; Harry, Elizabeth J.; Dixon, Nicholas E.; Beck, Jennifer L.; Kelso, Michael J.; Oakley, Aaron J.
Journal of Medicinal Chemistry, 2014 , vol. 57, # 6 p. 2799 - 2806

41979-39-94-氧代哌啶酮盐酸盐+108-23-6氯甲酸异丙酯→190013-27-54-氧代哌啶-1-羧酸异丙酯

参考文献

Mitsubishi Tanabe Pharma Corporation
Patent: EP2390254 A1, 2011 ;
Location in patent: Page/Page column 64 ;
EP 2390254 A1

41979-39-94-氧代哌啶酮盐酸盐+501-53-1氯甲酸苄酯→675-20-72-氮己环酮+19099-93-51-Cbz-4-哌啶酮

参考文献

Zeneca Limited
Patent: US5654299 A1, 1997 ;

41979-39-94-氧代哌啶酮盐酸盐→300715-96-21,3,4,5-四氢-吡啶并[4,3-b]吲哚-2,8-二羧酸 2-叔丁酯

参考文献

Ferguson, Fleur M.; Fedorov, Oleg; Chaikuad, Apirat; Philpott, Martin; Muniz, Joao R. C.; Felletar, Ildiko; Von Delft, Frank; Heightman, Tom; Knapp, Stefan; Abell, Chris; Ciulli, Alessio
Journal of Medicinal Chemistry, 2013 , vol. 56, # 24 p. 10183 - 10187

41979-39-94-氧代哌啶酮盐酸盐+350-46-9对氟硝基苯→23499-01-6

参考文献

Massa, S.; Mai, A.; Artico, M.
Synthetic Communications, 1990 , vol. 20, # 22 p. 3537 - 3545

41979-39-94-氧代哌啶酮盐酸盐→375853-82-01,2,3,6-四氢吡啶-4-硼酸频那醇酯

参考文献

Hoffmann-La Roche Inc.; Firooznia, Fariborz; Lin, Tai-An; Mertz, Eric; Sidduri, Achyutharao; So, Sung-Sau; Tilley, Jefferson Wright
Patent: US2013/150407 A1, 2013 ;

41979-39-94-氧代哌啶酮盐酸盐+82911-69-19-芴甲基-N-琥珀酰亚胺基碳酸酯→204376-55-6Fmoc-4-哌啶酮

参考文献

SANKARANARAYANAN, Alangudi
Patent: WO2005/33106 A1, 2005 ;
Location in patent: Page/Page column 61 ;
WO 2005/033106 A1

41979-39-94-氧代哌啶酮盐酸盐→183673-71-4N-BOC-4-氨基-4-羧酸哌啶

参考文献

Kiviranta, Paeivi H.; Leppaenen, Jukka; Rinne, Valtteri M.; Suuronen, Tiina; Kyrylenko, Olga; Kyrylenko, Sergiy; Kuusisto, Erkki; Tervo, Anu J.; Jaervinen, Tomi; Salminen, Antero; Poso, Antti; Wallen, Erik A.A.
Bioorganic and Medicinal Chemistry Letters, 2007 , vol. 17, # 9 p. 2448 - 2451

41979-39-94-氧代哌啶酮盐酸盐+124-63-0甲烷磺酰氯→218780-53-11-N-甲磺酰基-4-哌啶酮

参考文献

US2004/34008 A1, ;

Page/Page column 12 ;
US 20040034008 A1