4-氧代哌啶酮盐酸盐合成路线

79099-07-3N-叔丁氧羰基-4-哌啶酮→41979-39-94-氧代哌啶酮盐酸盐

参考文献

GLAXO GROUP LIMITED
Patent: WO2009/76387 A1, 2009 ;
Location in patent: Page/Page column 39-40 ;
WO 2009/076387 A1

3612-20-2N-苄基哌啶酮→41979-39-94-氧代哌啶酮盐酸盐

参考文献

Yoo, Kyung Ho; Choi, Hyun Sik; Kim, Dong Chan; Shin, Kye Jung; Kim, Dong Jin; Song, Yun Seon; Jin, Changbae
Archiv der Pharmazie, 2003 , vol. 336, # 4-5 p. 208 - 215

41979-39-94-氧代哌啶酮盐酸盐+105-34-0氰乙酸甲酯→1049767-69-22-氨基-4,5,6,7-四氢噻吩并[2,3-c]吡啶-3-羧酸甲酯盐酸盐

参考文献

MERCK PATENT GMBH; SCHULTZ, Melanie; SCHIEMANN, Kai; STAEHLE, Wolfgang
Patent: WO2010/112124 A1, 2010 ;
Location in patent: Page/Page column 66 ;
WO 2010/112124 A1

41979-39-94-氧代哌啶酮盐酸盐+138900-22-85-氯-1-(4-氟苯基)-1H-吲哚→106516-07-85-氯-1-(4-氟苯基)-3-(1,2,3,6-四氢吡啶-4-基)-1H-吲哚

参考文献

Perregaard; Arnt; Bogeso; Hyttel; Sanchez
Journal of Medicinal Chemistry, 1992 , vol. 35, # 6 p. 1092 - 1101

37089-77-33,3-二苯基丙酰氯+41979-39-94-氧代哌啶酮盐酸盐→105246-18-2

参考文献

Picard, Franck; Barassin, Stephan; Mokhtarian, Armand; Hartmann, Rolf W.
Journal of Medicinal Chemistry, 2002 , vol. 45, # 16 p. 3406 - 3417

41979-39-94-氧代哌啶酮盐酸盐→106516-54-5

参考文献

Perregaard; Arnt; Bogeso; Hyttel; Sanchez
Journal of Medicinal Chemistry, 1992 , vol. 35, # 6 p. 1092 - 1101

637-59-21-溴-3-苯基丙烷+41979-39-94-氧代哌啶酮盐酸盐→107100-64-1N-苯丙基-4-哌啶酮

参考文献

Heinrich-Pette-Institut; Julius-Maximilians-Universitaet Wuerzburg
Patent: EP2036556 A1, 2009 ;
Location in patent: Page/Page column 12 ;

41979-39-94-氧代哌啶酮盐酸盐+103-63-9(2-溴乙基)苯→39742-60-4N-(2-苯乙基)-4-哌啶酮

参考文献

AUSPEX PHARMACEUTICALS, INC.
Patent: US2010/16365 A1, 2010 ;
Location in patent: Page/Page column 19 ;
US 20100016365 A1

41979-39-94-氧代哌啶酮盐酸盐+122-78-1苯乙醛→39742-60-4N-(2-苯乙基)-4-哌啶酮

参考文献

Gupta, Pradeep Kumar; Ganesan, Kumaran; Pande, Ambuja; Malhotra, Ramesh Chandra
Journal of Chemical Research, 2005 , # 7 p. 452 - 453

41979-39-94-氧代哌啶酮盐酸盐+622-88-84-溴苯肼盐酸盐→497261-38-88-溴-2,3,4,5-四氢-1H-吡啶并[4,3-b]吲哚

参考文献

MIKANA THERAPEUTICS, INC.
Patent: WO2006/88949 A1, 2006 ;
Location in patent: Page/Page column 113; 114 ;