4,5-二氯-2-苄基-3(2H)-哒嗪合成路线 （共 7 条）
反应条件
potassium carbonate in N,N-dimethyl-formamide T=20°C; 16 h;
参考文献
Ewing, William R.; Zhu, Yeheng; Ellsworth, Bruce A.
Patent: US2006/287323 A1, 2006 ;
Location in patent: Page/Page column 12 ;
US 20060287323 A1
反应条件
potassium carbonate in dimethyl sulfoxide T=50 - 60°C; 7 h;
参考文献
Cho, Su-Dong; Kweon, Deok-Heon; Kang, Young-Jin; Chung, Hyun-A.; Yoon, Yong-Jin
Journal of Heterocyclic Chemistry, 1998 , vol. 35, # 3 p. 601 - 605
反应条件
in 1,4-dioxane; methanol
T=20°C; 1.16667 h;
参考文献
Ewing, William R.; Zhu, Yeheng; Ellsworth, Bruce A.
Patent: US2006/287323 A1, 2006 ;
Location in patent: Page/Page column 12 ;
US 20060287323 A1
反应条件
sodium methylate in 1,4-dioxane
T=20°C; 1 h;
参考文献
Miao, Zhenwei; Sun, Ying; Nakajima, Suanne; Tang, Datong; Wu, Frank; Xu, Guoyou; Or, Yat S.; Wang, Zhe
Patent: US2005/153877 A1, 2005 ;
Location in patent: Page/Page column 165-166 ;
US 20050153877 A1
反应条件
hydrogen iodide
24 h; Heating;
参考文献
Coelho, Alberto; Sotelo, Eddy; Novoa, Hector; Peeters, Oswald M.; Blaton, Norbert; Ravina, Enrique
Tetrahedron, 2004 , vol. 60, # 52 p. 12177 - 12189
反应条件
1: 88 percent / hydriodic acid / 24 h / Heating
2: 78 percent / bis(triphenylphosphine)palladium(II) dichloride / toluene / Heating
View Scheme
参考文献
Coelho, Alberto; Sotelo, Eddy; Novoa, Hector; Peeters, Oswald M.; Blaton, Norbert; Ravina, Enrique
Tetrahedron, 2004 , vol. 60, # 52 p. 12177 - 12189
反应条件
in methanol
10 h; Ambient temperature;
参考文献
Cho, Su-Dong; Kweon, Deok-Heon; Kang, Young-Jin; Chung, Hyun-A.; Yoon, Yong-Jin
Journal of Heterocyclic Chemistry, 1998 , vol. 35, # 3 p. 601 - 605
