1,3,4,5-四氢-2H-1,3-苯并二氮杂卓-2-酮合成路线 （共 6 条）
反应条件
in tetrahydrofuran
T=0 - 20°C; 43 h; Heating / reflux;
参考文献
WARNER-LAMBERT COMPANY LLC
Patent: WO2004/69245 A1, 2004 ;
Location in patent: Page/Page column 86 ;
反应条件
1-methyl-pyrrolidin-2-one; selenium in tetrahydrofuran
T=15°C; P=735.5 Torr; 1 h;
参考文献
Yoshida, Tohru; Kambe, Nobuaki; Murai, Shinji; Sonoda, Noboru
Bulletin of the Chemical Society of Japan, 1987 , vol. 60, p. 1793 - 1800
反应条件
lithium diisopropyl amide in tetrahydrofuran; hexane
T=-78°C; Reflux;
参考文献
Dengiz, Cagatay; Oezcan, Sevil; Sahin, Ertan; Balci, Metin
Synthesis, 2010 , # 8 art. no. P16809SS, p. 1365 - 1370
反应条件
trifluoroacetic acid in dichloromethane
T=0 - 20°C;
参考文献
Dengiz, Cagatay; Oezcan, Sevil; Sahin, Ertan; Balci, Metin
Synthesis, 2010 , # 8 art. no. P16809SS, p. 1365 - 1370
反应条件
N-methyl-pyrrolidine; selenium; air
1.) THF, 100 deg C, 30 kg/cm2, 20 h, 2.) 1 h; Yield given. Multistep reaction;
参考文献
Yoshida, Tohru; Kambe, Nobuaki; Murai, Shinji; Sonoda, Noboru
Tetrahedron Letters, 1986 , vol. 27, # 26 p. 3037 - 3040
反应条件
1: selenium
2: O2
View Scheme
参考文献
Yoshida, Tohru; Kambe, Nobuaki; Ogawa, Akiya; Sonoda, Noboru
Phosphorus and Sulfur and the Related Elements, 1988 , vol. 38, p. 137 - 148
