邻苯二甲酰基-L-丙氨酸合成路线 (共 17 条)
反应条件
in water 0.5 h; microwave irradiation;
参考文献
Shendage, Deepak M.; Froehlich, Roland; Haufe, Guenter
Organic Letters, 2004 , vol. 6, # 21 p. 3675 - 3678
反应条件
sodium carbonate in water T=20°C; 3 h;
参考文献
Zhang, Qi; Chen, Kai; Rao, Weihao; Zhang, Yuejun; Chen, Fa-Jie; Shi, Bing-Feng
Angewandte Chemie - International Edition, 2013 , vol. 52, # 51 p. 13588 - 13592
Angew. Chem., 2013 , vol. 125, # 51 p. 13833 - 13837,5
反应条件
hydrogen; palladium on activated charcoal in methanol
参考文献
Kubo, Akira; Kubota, Hitoshi; Takahashi, Masami; Nunami, Ken-Ichi
Tetrahedron Letters, 1996 , vol. 37, # 28 p. 4957 - 4960
参考文献
Al-Farhan, Khalid; Ghazzali, Mohamed; Al-Hazimi, Hassan M.A.; El-Faham, Ayman; Reedijk, Jan
Journal of Molecular Structure, 2011 , vol. 994, # 1-3 p. 269 - 275
反应条件
1: 90 percent / various solvent(s) / 12 h / 25 °C 2: 72 percent / diethyl ether / 0.5 h / -20 °C 3: 95 percent / H2 / Pd/C / methanol View Scheme
参考文献
Kubo, Akira; Kubota, Hitoshi; Takahashi, Masami; Nunami, Ken-Ichi
Tetrahedron Letters, 1996 , vol. 37, # 28 p. 4957 - 4960
反应条件
1: 72 percent / diethyl ether / 0.5 h / -20 °C 2: 95 percent / H2 / Pd/C / methanol View Scheme
参考文献
Kubo, Akira; Kubota, Hitoshi; Takahashi, Masami; Nunami, Ken-Ichi
Tetrahedron Letters, 1996 , vol. 37, # 28 p. 4957 - 4960
反应条件
2,6-di-tert-butyl-pyridine; 2-hydroxy-1,3-dimethylbenzene; C32H12BF24(1-)*C52H34N2O2P(1+) in toluene T=0°C; 0.3 h; Inert atmosphere; optical yield given as percent eeenantioselective reaction;
参考文献
Uraguchi, Daisuke; Kinoshita, Natsuko; Ooi, Takashi
Journal of the American Chemical Society, 2010 , vol. 132, # 35 p. 12240 - 12242
反应条件
1: ethylene glycol dimethyl ether / 5 h / Reflux 2: sodium acetate; acetic anhydride / 2 h / Reflux View Scheme
参考文献
El-Zahabi, Mohamed A.; Gad, Laila M.; Bamanie, Faida H.; Al-Marzooki, Zohair
Medicinal Chemistry Research, 2012 , vol. 21, # 1 p. 75 - 84
反应条件
sodium acetate; acetic anhydride 2 h; Reflux;
参考文献
El-Zahabi, Mohamed A.; Gad, Laila M.; Bamanie, Faida H.; Al-Marzooki, Zohair
Medicinal Chemistry Research, 2012 , vol. 21, # 1 p. 75 - 84
反应条件
in acetone 3 h; Irradiation;
参考文献
Sato, Yasuhiko; Nakai, Hideo; Mizoguchi, Tomishige; Kawanishi, Masazumi; Hatanaka, Yasumaru; Kanaoka, Yuichi
Chemical & Pharmaceutical Bulletin, 1982 , vol. 30, # 4 p. 1263 - 1270