1,1-二甲酸乙酯环戊烷合成路线 （共 39 条）
反应条件
1: 95 percent / 10percent aq. NaOH / 5 h
2: 92 percent / SOCl2 / 3 h
View Scheme
参考文献
Sartori, Giovanni; Bigi, Franca; Goffredi, Gino; Maggi, Raimondo; Portioli, Roberto; Casnati, Giuseppe
Journal of Chemical Research, Miniprint, 1993 , # 8 p. 2061 - 2079
反应条件
1: 85 percent / LiAlH4
4: LiAlH4
View Scheme
参考文献
Houk,J.; Whitesides,G.M.
Journal of the American Chemical Society, 1987 , vol. 109, p. 6825
反应条件
sodium hydroxide
5 h;
参考文献
Sartori, Giovanni; Bigi, Franca; Goffredi, Gino; Maggi, Raimondo; Portioli, Roberto; Casnati, Giuseppe
Journal of Chemical Research, Miniprint, 1993 , # 8 p. 2061 - 2079
反应条件
1: 85 percent / LiAlH4
View Scheme
参考文献
BETA PHARMA CANADA INC; ASTAR BIOTECH LLC; WANG, Zhaoyin; LI, Lianhai
Patent: WO2013/185202 A1, 2013 ;
反应条件
potassium hydroxide in ethanol
Ambient temperature;
参考文献
Paulsen, Hans; Maass, Uwe
Chemische Berichte, 1981 , vol. 114, # 1 p. 346 - 358
反应条件
hydrogenchloride in ethanol; water
参考文献
Boehringer Mannheim Italia S.p.A.
Patent: US5453423 A1, 1995 ;
参考文献
Bailey,W.J.; Daly,J.J.
Journal of Organic Chemistry, 1964 , vol. 29, p. 1249 - 1251
反应条件
hydrogenchloride; sodium ethanolate in ethanol
T=80°C; 2 h; Heating;
参考文献
McKeown, Robert H.; Prankerd, Richard J.
Journal of the Chemical Society, Perkin Transactions 2: Physical Organic Chemistry (1972-1999), 1981 , p. 481 - 487
反应条件
sodium ethanolate; urea
参考文献
E. Lilly and Co.
Patent: US2621183 , 1951 ;
