5,6-二氯烟酸合成路线

参考文献

Exelixis, Inc.
Patent: US2010/249071 A1, 2010 ;
Location in patent: Page/Page column 42-43 ;

参考文献

Bach, Peter; Bostroem, Jonas; Brickmann, Kay; Van Giezen; Groneberg, Robert D.; Harvey, Darren M.; O'Sullivan, Michael; Zetterberg, Fredrik
European Journal of Medicinal Chemistry, 2013 , vol. 65, p. 360 - 375

110-85-0哌嗪+

41667-95-25,6-二氯烟酸

889953-74-65-氯-6-吡嗪基-1-烟酸

参考文献

Bach, Peter; Bostroem, Jonas; Brickmann, Kay; Van Giezen; Groneberg, Robert D.; Harvey, Darren M.; O'Sullivan, Michael; Zetterberg, Fredrik
European Journal of Medicinal Chemistry, 2013 , vol. 65, p. 360 - 375

41667-95-25,6-二氯烟酸

54127-29-62,3-二氯吡啶-5-羰酰氯

参考文献

PFIZER PRODUCTS INC.
Patent: WO2007/36769 A1, 2007 ;
Location in patent: Page/Page column 45 ;